Hypothalamic hamartoma and gelastic epilepsy: a case report.

Y. Y. Lin, C. H. Yiu, S. Y. Kwan, Y. F. Tu, Tai-Tong Wong, K. P. Chang, M. S. Su

Research output: Contribution to journalArticle

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Abstract

We studied a 6-year-old girl who presented with inappropriate and uncontrollable laughing episodes since age 3. Physical examination revealed a precocious puberty. The luteinizing hormone-releasing hormone (LH-RH) stimulation test showed an increased level of follicle-stimulating hormone (FSH). The interictal electroencephalogram (EEG) was normal. Several laughing fits were documented during video/EEG monitoring. During laughing, the ictal EEG showed a diffuse suppression of background rhythm, prominent over the left mesial temporal region. A mass lesion about 2 x 2 cm in size was found over the suprasellar cistern with a broad base attached to the hypothalamus, which was isodense on a computed tomography (CT) scan, isointense to gray matter on T1-weighted magnetic resonance (MR) imaging and hyperintense on T2-weighted MR imaging. The findings were suggestive of a hypothalamic hamartoma. A variety of anticonvulsants had been used with little or no response to the frequency or duration of the laughing seizures.

Original languageEnglish
Pages (from-to)78-82
Number of pages5
JournalZhonghua yi xue za zhi Chinese medical journal; Free China ed
Volume55
Issue number1
Publication statusPublished - Jan 1 1995
Externally publishedYes

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Partial Epilepsy
Electroencephalography
Magnetic Resonance Imaging
Precocious Puberty
Follicle Stimulating Hormone
Temporal Lobe
Gonadotropin-Releasing Hormone
Anticonvulsants
Hypothalamus
Physical Examination
Seizures
Stroke
Tomography
Hypothalamic hamartomas

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lin, Y. Y., Yiu, C. H., Kwan, S. Y., Tu, Y. F., Wong, T-T., Chang, K. P., & Su, M. S. (1995). Hypothalamic hamartoma and gelastic epilepsy: a case report. Zhonghua yi xue za zhi Chinese medical journal; Free China ed, 55(1), 78-82.

Hypothalamic hamartoma and gelastic epilepsy : a case report. / Lin, Y. Y.; Yiu, C. H.; Kwan, S. Y.; Tu, Y. F.; Wong, Tai-Tong; Chang, K. P.; Su, M. S.

In: Zhonghua yi xue za zhi Chinese medical journal; Free China ed, Vol. 55, No. 1, 01.01.1995, p. 78-82.

Research output: Contribution to journalArticle

Lin, YY, Yiu, CH, Kwan, SY, Tu, YF, Wong, T-T, Chang, KP & Su, MS 1995, 'Hypothalamic hamartoma and gelastic epilepsy: a case report.', Zhonghua yi xue za zhi Chinese medical journal; Free China ed, vol. 55, no. 1, pp. 78-82.
Lin, Y. Y. ; Yiu, C. H. ; Kwan, S. Y. ; Tu, Y. F. ; Wong, Tai-Tong ; Chang, K. P. ; Su, M. S. / Hypothalamic hamartoma and gelastic epilepsy : a case report. In: Zhonghua yi xue za zhi Chinese medical journal; Free China ed. 1995 ; Vol. 55, No. 1. pp. 78-82.
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