Hyperthyroidism and concurrent thyroid cancer

F. F. Chou, S. M. Sheen-Chen, Y. S. Chen, M. J. Chen

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A total of 14 patients had hyperthyroidism coexisting with thyroid malignancy. Twelve patients had papillary cancer, 1 follicular cancer and 1 anaplastic cancer. Patients with Graves' disease had a low rate of associated malignancy 1.5% (10/674) and toxic nodular goiter had an incidence of 3.1% (4/27). Subtotal thyroidectomy was performed in 11 patients, total thyroidectomy in 2 and biopsy only in 1. Two of the subtotal thyroidectomy groups had to be operated on again due to their size being over 1 cm. In the follow-up period, only one patient died of anaplastic cancer in the second month. One patient who had multiple foci of the papillary cancer had local recurrence and lymphnode metastasis 27 months later, and needed another radical neck dissection. All the other 12 patients were doing well without cancer recurrence. In conclusion, hyperthyroidism may have a malignancy of 1.75% (14/801). Subtotal thyroidectomy is adequate for occult cancer. Those patients with multiple foci, cancer size over 1 cm and capsule invasion should have a second operation with total thyroidectomy.

Original languageEnglish
Pages (from-to)343-346
Number of pages4
JournalInternational Surgery
Volume78
Issue number4
Publication statusPublished - Dec 1 1993
Externally publishedYes

Fingerprint

Hyperthyroidism
Thyroid Neoplasms
Thyroidectomy
Neoplasms
Nodular Goiter
Recurrence
Neck Dissection
Second Primary Neoplasms
Poisons
Graves Disease
Capsules
Thyroid Gland
Neoplasm Metastasis
Biopsy
Incidence

Keywords

  • hyperthyroidism
  • reoperation
  • thyroid neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Chou, F. F., Sheen-Chen, S. M., Chen, Y. S., & Chen, M. J. (1993). Hyperthyroidism and concurrent thyroid cancer. International Surgery, 78(4), 343-346.

Hyperthyroidism and concurrent thyroid cancer. / Chou, F. F.; Sheen-Chen, S. M.; Chen, Y. S.; Chen, M. J.

In: International Surgery, Vol. 78, No. 4, 01.12.1993, p. 343-346.

Research output: Contribution to journalArticle

Chou, FF, Sheen-Chen, SM, Chen, YS & Chen, MJ 1993, 'Hyperthyroidism and concurrent thyroid cancer', International Surgery, vol. 78, no. 4, pp. 343-346.
Chou FF, Sheen-Chen SM, Chen YS, Chen MJ. Hyperthyroidism and concurrent thyroid cancer. International Surgery. 1993 Dec 1;78(4):343-346.
Chou, F. F. ; Sheen-Chen, S. M. ; Chen, Y. S. ; Chen, M. J. / Hyperthyroidism and concurrent thyroid cancer. In: International Surgery. 1993 ; Vol. 78, No. 4. pp. 343-346.
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