Hyperthermia therapy for low blood supplied tumors: A model of computer simulation

Cheng Jeng Tai, Wei Hsu Wang, Po Min Chen, Jui Chien Hsieh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The blood perfusion of some tumors is relatively low and poorly responsive to hyperthermia therapy. As a result, the blood flow provides relatively little heat sinking for tumors. We hypothesized that the thermal gradient between tumors and normal tissues could be increased by applying energy only during the pulsation of arteries. Tests of the hypothesis were done by using a finite element model, which simulated a tumor surrounded by normal tissues and this tumor received either continuous or pulsatile heat, together with the pulsatile blood flow. Our results indicated there was a thermal gradient of 8 °C between pulsatile and continuous powers on heat delivery. Established values for tissues and tumors were incorporated into this model and it facilitated us to predict the possible results on hyperthermia therapy.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages1271
Number of pages1
Volume2
ISBN (Print)0780356756
Publication statusPublished - 1999
Externally publishedYes
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

ASJC Scopus subject areas

  • Bioengineering

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  • Cite this

    Tai, C. J., Wang, W. H., Chen, P. M., & Hsieh, J. C. (1999). Hyperthermia therapy for low blood supplied tumors: A model of computer simulation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 2, pp. 1271). IEEE.