Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai

Yuan Bin Cheng, Ahmed Eid Fazary, Yu Chi Lin, I. Wen Lo, Seow Chin Ong, Shun Ying Chen, Ching Te Chien, Yen Jung Lin, Wan Wan Lin, Ya Ching Shen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.

Original languageEnglish
Pages (from-to)727-734
Number of pages8
JournalNatural Product Research
Volume27
Issue number8
DOIs
Publication statusPublished - Apr 1 2013

Keywords

  • anti-inflammatory activity
  • Hypericum nakamurai
  • phloroglucinols

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Analytical Chemistry
  • Organic Chemistry

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  • Cite this

    Cheng, Y. B., Fazary, A. E., Lin, Y. C., Lo, I. W., Ong, S. C., Chen, S. Y., Chien, C. T., Lin, Y. J., Lin, W. W., & Shen, Y. C. (2013). Hyperinakin, a new anti-inflammatory phloroglucinol derivative from Hypericum nakamurai. Natural Product Research, 27(8), 727-734. https://doi.org/10.1080/14786419.2012.695365