Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report

I. Han Chiang, Yi Shu Liao, Niann Tzyy Dai, Hao Yu Chiao, Chang Yi Chou, Shyi Gen Chen, Tim Mo Chen, Shun Cheng Chang

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion. Management usually consists of systemic drug therapy, such as corticosteroids, sulfones, or immunosuppressants, either alone or in combination. Long-term use of these medications often has untold side effects. Hyperbaric oxygen therapy (HBOT) has been shown effective in the treatment of PG, reducing pain and tempering the need for medication. A case is presented of a 54-year-old woman with diabetes, hypertension, and a peptic ulcer who presented with painful, purulent ulcers on her buttocks, hands, and lower extremities of 2 weeks' duration. She was ultimately diagnosed with PG and provided 20 mg/day of oral prednisone for 1 week, tapered to 10 mg/day in the next week and then stopped. In addition, she received 12 sessions of HBOT-she breathed in 100% oxygen under 2.5 atmospheres absolute pressure for 90 minutes over 2 weeks. Her wounds healed without scarring. This excellent outcome including good wound healing, decreased pain, and reduced doses of systemic corticosteroids warrants additional study of the adjunctive use of HBOT for PG.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalOstomy Wound Management
Volume62
Issue number5
Publication statusPublished - May 1 2016

Fingerprint

Pyoderma Gangrenosum
Hyperbaric Oxygenation
Adrenal Cortex Hormones
Pain
Sulfones
Buttocks
Therapeutics
Immunosuppressive Agents
Prednisone
Peptic Ulcer
Atmosphere
Skin Diseases
Wound Healing
Ulcer
Cicatrix
Lower Extremity
Hand
Oxygen
Hypertension
Pressure

Keywords

  • Case reports
  • hyperbaric oxygenation
  • neutrophilic dermatosis
  • pyoderma gangrenosum
  • skin diseases

ASJC Scopus subject areas

  • Internal Medicine
  • Nursing(all)
  • Gastroenterology

Cite this

Chiang, I. H., Liao, Y. S., Dai, N. T., Chiao, H. Y., Chou, C. Y., Chen, S. G., ... Chang, S. C. (2016). Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report. Ostomy Wound Management, 62(5), 32-36.

Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum : A Case Report. / Chiang, I. Han; Liao, Yi Shu; Dai, Niann Tzyy; Chiao, Hao Yu; Chou, Chang Yi; Chen, Shyi Gen; Chen, Tim Mo; Chang, Shun Cheng.

In: Ostomy Wound Management, Vol. 62, No. 5, 01.05.2016, p. 32-36.

Research output: Contribution to journalReview article

Chiang, IH, Liao, YS, Dai, NT, Chiao, HY, Chou, CY, Chen, SG, Chen, TM & Chang, SC 2016, 'Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report', Ostomy Wound Management, vol. 62, no. 5, pp. 32-36.
Chiang IH, Liao YS, Dai NT, Chiao HY, Chou CY, Chen SG et al. Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report. Ostomy Wound Management. 2016 May 1;62(5):32-36.
Chiang, I. Han ; Liao, Yi Shu ; Dai, Niann Tzyy ; Chiao, Hao Yu ; Chou, Chang Yi ; Chen, Shyi Gen ; Chen, Tim Mo ; Chang, Shun Cheng. / Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum : A Case Report. In: Ostomy Wound Management. 2016 ; Vol. 62, No. 5. pp. 32-36.
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