How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences

Alexander Heinzel, Felix Bermpohl, Robert Niese, Andrea Pfennig, Alvaro Pascual-Leone, Gottfried Schlaug, Georg Northoff

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

One of the major problems in affective neuroscience of healthy subjects as well as of patients with emotional dysfunctions is to disentangle emotional core functions and non-emotional processes. Emotional valence is considered an emotional key process. The present study employed a parametric functional magnetic resonance imaging (fMRI) study to address this question. Thirteen healthy volunteers were scanned during emotional stimulus processing (International Affective Picture System). The presented pictures covered the entire range of emotional valences. The fMRI data were consecutively subjected to a preliminary categorical (valence-independent) and a detailed parametric analysis, the latter using individual valence ratings as regressor. The parametric analysis revealed a linear valence-dependent modulation of the BOLD signal in the orbito- and dorsomedial prefrontal cortex (OMPFC, DMPFC), medial parietal cortex (MPC), and insula. In addition, we observed that emotional valence exerts its effects predominantly via modulation of signal decreases. We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions.

Original languageEnglish
Pages (from-to)348-358
Number of pages11
JournalCognitive Brain Research
Volume25
Issue number1
DOIs
Publication statusPublished - Sep 2005
Externally publishedYes

Fingerprint

Healthy Volunteers
Emotions
Magnetic Resonance Imaging
Parietal Lobe
Neurosciences
Prefrontal Cortex
Psychology

Keywords

  • Baseline
  • Cortical midline region
  • Emotion
  • IAPS
  • Valence

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology

Cite this

How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences. / Heinzel, Alexander; Bermpohl, Felix; Niese, Robert; Pfennig, Andrea; Pascual-Leone, Alvaro; Schlaug, Gottfried; Northoff, Georg.

In: Cognitive Brain Research, Vol. 25, No. 1, 09.2005, p. 348-358.

Research output: Contribution to journalArticle

Heinzel, Alexander ; Bermpohl, Felix ; Niese, Robert ; Pfennig, Andrea ; Pascual-Leone, Alvaro ; Schlaug, Gottfried ; Northoff, Georg. / How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences. In: Cognitive Brain Research. 2005 ; Vol. 25, No. 1. pp. 348-358.
@article{37a25e4101fc4ef9ae917ed1d91a6022,
title = "How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences",
abstract = "One of the major problems in affective neuroscience of healthy subjects as well as of patients with emotional dysfunctions is to disentangle emotional core functions and non-emotional processes. Emotional valence is considered an emotional key process. The present study employed a parametric functional magnetic resonance imaging (fMRI) study to address this question. Thirteen healthy volunteers were scanned during emotional stimulus processing (International Affective Picture System). The presented pictures covered the entire range of emotional valences. The fMRI data were consecutively subjected to a preliminary categorical (valence-independent) and a detailed parametric analysis, the latter using individual valence ratings as regressor. The parametric analysis revealed a linear valence-dependent modulation of the BOLD signal in the orbito- and dorsomedial prefrontal cortex (OMPFC, DMPFC), medial parietal cortex (MPC), and insula. In addition, we observed that emotional valence exerts its effects predominantly via modulation of signal decreases. We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions.",
keywords = "Baseline, Cortical midline region, Emotion, IAPS, Valence",
author = "Alexander Heinzel and Felix Bermpohl and Robert Niese and Andrea Pfennig and Alvaro Pascual-Leone and Gottfried Schlaug and Georg Northoff",
year = "2005",
month = "9",
doi = "10.1016/j.cogbrainres.2005.06.009",
language = "English",
volume = "25",
pages = "348--358",
journal = "Cognitive Brain Research",
issn = "0926-6410",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - How do we modulate our emotions? Parametric fMRI reveals cortical midline structures as regions specifically involved in the processing of emotional valences

AU - Heinzel, Alexander

AU - Bermpohl, Felix

AU - Niese, Robert

AU - Pfennig, Andrea

AU - Pascual-Leone, Alvaro

AU - Schlaug, Gottfried

AU - Northoff, Georg

PY - 2005/9

Y1 - 2005/9

N2 - One of the major problems in affective neuroscience of healthy subjects as well as of patients with emotional dysfunctions is to disentangle emotional core functions and non-emotional processes. Emotional valence is considered an emotional key process. The present study employed a parametric functional magnetic resonance imaging (fMRI) study to address this question. Thirteen healthy volunteers were scanned during emotional stimulus processing (International Affective Picture System). The presented pictures covered the entire range of emotional valences. The fMRI data were consecutively subjected to a preliminary categorical (valence-independent) and a detailed parametric analysis, the latter using individual valence ratings as regressor. The parametric analysis revealed a linear valence-dependent modulation of the BOLD signal in the orbito- and dorsomedial prefrontal cortex (OMPFC, DMPFC), medial parietal cortex (MPC), and insula. In addition, we observed that emotional valence exerts its effects predominantly via modulation of signal decreases. We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions.

AB - One of the major problems in affective neuroscience of healthy subjects as well as of patients with emotional dysfunctions is to disentangle emotional core functions and non-emotional processes. Emotional valence is considered an emotional key process. The present study employed a parametric functional magnetic resonance imaging (fMRI) study to address this question. Thirteen healthy volunteers were scanned during emotional stimulus processing (International Affective Picture System). The presented pictures covered the entire range of emotional valences. The fMRI data were consecutively subjected to a preliminary categorical (valence-independent) and a detailed parametric analysis, the latter using individual valence ratings as regressor. The parametric analysis revealed a linear valence-dependent modulation of the BOLD signal in the orbito- and dorsomedial prefrontal cortex (OMPFC, DMPFC), medial parietal cortex (MPC), and insula. In addition, we observed that emotional valence exerts its effects predominantly via modulation of signal decreases. We conclude that the psychological concept of emotional valence may be related to neural processing in cortical midline regions.

KW - Baseline

KW - Cortical midline region

KW - Emotion

KW - IAPS

KW - Valence

UR - http://www.scopus.com/inward/record.url?scp=24644478519&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=24644478519&partnerID=8YFLogxK

U2 - 10.1016/j.cogbrainres.2005.06.009

DO - 10.1016/j.cogbrainres.2005.06.009

M3 - Article

C2 - 16081255

AN - SCOPUS:24644478519

VL - 25

SP - 348

EP - 358

JO - Cognitive Brain Research

JF - Cognitive Brain Research

SN - 0926-6410

IS - 1

ER -