Horseradish peroxidase localization of the sympathetic postganglionic neurons innervating the cat heart

Chun Jen Shih, King Shun Chuang, Shin Han Tsai, Jiang Chuan Liu

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The localization of the sympathetic postganglionic neurons innervating the cat heart has been investigated by using retrograde axonal transport of horseradish peroxidase (HRP). HRP was injected into the subepicardial layers of 4 different cardiac regions. The animals were sacrificed 72-96 h later and fixed by perfusion via the left ventricle. The paravertebral sympathetic ganglia from the superior cervical, middle cervical and stellate ganglia to T10 ganglia were removed and processed for HRP identification. Following injections of HRP into the apex of the heart, the sinoatrial (SA) nodal region and the ventral wall of the right ventricle, we observed that HRP-labeled sympathetic neurons were localized predominantly in the right stellate ganglia, and to a lesser extent, in the right superior and middle cervical ganglia, and left stellate ganglia. Fewer labeled cells were found in the right T4-T6. T8 and T9. After HRP injection into the dorsal wall of the left ventricle, HRP-labeled cells were present mainly in the left stellate ganglia.

Original languageEnglish
Pages (from-to)179-189
Number of pages11
JournalJournal of the Autonomic Nervous System
Volume13
Issue number3
DOIs
Publication statusPublished - 1985
Externally publishedYes

Fingerprint

Horseradish Peroxidase
Cats
Stellate Ganglion
Neurons
Heart Ventricles
Superior Cervical Ganglion
Sympathetic Ganglia
Injections
Axonal Transport
Ganglia
Perfusion

Keywords

  • heart
  • horseradish peroxidase (HRP)
  • sinoatrial node
  • stellate ganglion
  • sympathetic neurons

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Horseradish peroxidase localization of the sympathetic postganglionic neurons innervating the cat heart. / Shih, Chun Jen; Chuang, King Shun; Tsai, Shin Han; Liu, Jiang Chuan.

In: Journal of the Autonomic Nervous System, Vol. 13, No. 3, 1985, p. 179-189.

Research output: Contribution to journalArticle

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