Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery

Hong Yuan Lian, Ming Hu, Chia Hung Liu, Yusuke Yamauchi, Kevin C.W. Wu

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC 50 > 1000 μg mL -1) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.

Original languageEnglish
Pages (from-to)5151-5153
Number of pages3
JournalChemical Communications
Volume48
Issue number42
DOIs
Publication statusPublished - May 25 2012

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Chemotherapy
Drug delivery
Cisplatin
Capsules
Polymers
Nanoparticles
Pharmaceutical Preparations
ferric ferrocyanide

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery. / Lian, Hong Yuan; Hu, Ming; Liu, Chia Hung; Yamauchi, Yusuke; Wu, Kevin C.W.

In: Chemical Communications, Vol. 48, No. 42, 25.05.2012, p. 5151-5153.

Research output: Contribution to journalArticle

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