Hepatoprotection by "Dangqui-Long-Hwei-Wan" in male mice

Jay Ho Chen, Hsiu O. Ho, Kun Ying Yen, Ling-Ling Yang

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Abstract

Dangqui-Long-Hwei -Wan (D.L.H.W.) is a traditional Chinese prescription for treatment of hepatitis. The hepatoprotective effects of D.L.H.W. and its constituents were investigated on carbon tetrachloride-induced liver damage mice. The hepatoprotective effect is more prominent for aqueous extracts of the complete formula of D.L.H.W., especially the one cited in the Chinese medical book Hsuan-Ming-Lun (H.M.L.). Our results are in accordance with those described in the Chinese medical literature and the indications suggested in clinical treatment (Wang, 1982). The results further indicate that Scutellariae Radix plays an important role in the hepatoprotective activity. Moschus could be omitted from D.L.H.W. with no significant influence on its effect. The underlying mechanism for the hepatoprotective effect of D.L.H.W. possibly results from the inhibition of the formation of ·CCl 3 and the enhancement of immunity of hepatitis-carrying patients.

Original languageEnglish
Pages (from-to)115-121
Number of pages7
JournalAmerican Journal of Chinese Medicine
Volume28
Issue number1
Publication statusPublished - 2000

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ASJC Scopus subject areas

  • Complementary and alternative medicine

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