Hemopoietic stem cells in human peripheral blood

Ronald D. Barr; Jacqueline Whang-Peng; Seymour Perry

doi:10.1126/science.1179209

Hemopoietic stem cells in human peripheral blood

Ronald D. Barr, Jacqueline Whang-Peng, Seymour Perry

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94 Citations (Scopus)

Abstract

A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the resetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.

Original language	English
Pages (from-to)	284-285
Number of pages	2
Journal	Science
Volume	190
Issue number	4211
DOIs	https://doi.org/10.1126/science.1179209
Publication status	Published - Jan 1 1975
Externally published	Yes

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Barr, R. D., Whang-Peng, J., & Perry, S. (1975). Hemopoietic stem cells in human peripheral blood. Science, 190(4211), 284-285. https://doi.org/10.1126/science.1179209

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Access to Document

10.1126/science.1179209