Hemopoietic stem cells in human peripheral blood

Ronald D. Barr, Jacqueline Whang-Peng, Seymour Perry

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the resetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.

Original languageEnglish
Pages (from-to)284-285
Number of pages2
JournalScience
Volume190
Issue number4211
DOIs
Publication statusPublished - Jan 1 1975
Externally publishedYes

Fingerprint

Blood Cells
Stem Cells
Lymphocytes
T-Lymphocytes
Population

ASJC Scopus subject areas

  • General

Cite this

Hemopoietic stem cells in human peripheral blood. / Barr, Ronald D.; Whang-Peng, Jacqueline; Perry, Seymour.

In: Science, Vol. 190, No. 4211, 01.01.1975, p. 284-285.

Research output: Contribution to journalArticle

Barr, Ronald D. ; Whang-Peng, Jacqueline ; Perry, Seymour. / Hemopoietic stem cells in human peripheral blood. In: Science. 1975 ; Vol. 190, No. 4211. pp. 284-285.
@article{89f3dcdb0e5849e0abb82167f8142a8c,
title = "Hemopoietic stem cells in human peripheral blood",
abstract = "A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the resetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.",
author = "Barr, {Ronald D.} and Jacqueline Whang-Peng and Seymour Perry",
year = "1975",
month = "1",
day = "1",
doi = "10.1126/science.1179209",
language = "English",
volume = "190",
pages = "284--285",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "4211",

}

TY - JOUR

T1 - Hemopoietic stem cells in human peripheral blood

AU - Barr, Ronald D.

AU - Whang-Peng, Jacqueline

AU - Perry, Seymour

PY - 1975/1/1

Y1 - 1975/1/1

N2 - A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the resetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.

AB - A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the resetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.

UR - http://www.scopus.com/inward/record.url?scp=0016824304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016824304&partnerID=8YFLogxK

U2 - 10.1126/science.1179209

DO - 10.1126/science.1179209

M3 - Article

C2 - 1179209

AN - SCOPUS:0016824304

VL - 190

SP - 284

EP - 285

JO - Science

JF - Science

SN - 0036-8075

IS - 4211

ER -