Hemolysis following correction of ventricular septal defect.

H. Chang, C. R. Hung, F. Y. Huang, G. J. Wu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Hemolysis following repair of a ventricular septal defect (VSD) is an unusual complication. Three cases of patients who had simple VSD are described here. After repair of the VSD, the postoperative course was complicated by the intravascular hemolysis induced by the interaction between the red blood cells and the double velour Dacron patch. Thus the patients' hemodynamic status deteriorated. The first 2 patients had a course of hemoglobinuria, hyperamylasemia, hyperglycemia, malignant hypertension, hepatospenomegaly, acute renal failure and hypertensive encephalopathy. One patient, who did not undergo reoperation, died due to multiple organ failure; the other one, who underwent operation revision in order to arrest the hemolysis, died of sepsis. Early reoperation was performed in the remaining patient to replace the double velour Dacron patch with a pericardium-covered knitted Dacron patch, and he survived. Hemolysis ceased in both patients who had the double velour Dacron patch replaced with a pericardium-covered patch. A review of the literature failed to show previous reports concerned with hemolysis associated with repair of a simple VSD. We now report what we believe to be the first cases in the literature with this unique clinical course following hemolysis.

Original languageEnglish
Pages (from-to)1004-1008
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume89
Issue number11
Publication statusPublished - Nov 1990
Externally publishedYes

Fingerprint

Ventricular Heart Septal Defects
Hemolysis
Polyethylene Terephthalates
Pericardium
Reoperation
Hypertensive Encephalopathy
Hemoglobinuria
Hyperamylasemia
Malignant Hypertension
Multiple Organ Failure
Acute Kidney Injury
Hyperglycemia
Sepsis
Erythrocytes
Hemodynamics
velour

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hemolysis following correction of ventricular septal defect. / Chang, H.; Hung, C. R.; Huang, F. Y.; Wu, G. J.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 89, No. 11, 11.1990, p. 1004-1008.

Research output: Contribution to journalArticle

@article{1c663f0821e6432f9560078935537825,
title = "Hemolysis following correction of ventricular septal defect.",
abstract = "Hemolysis following repair of a ventricular septal defect (VSD) is an unusual complication. Three cases of patients who had simple VSD are described here. After repair of the VSD, the postoperative course was complicated by the intravascular hemolysis induced by the interaction between the red blood cells and the double velour Dacron patch. Thus the patients' hemodynamic status deteriorated. The first 2 patients had a course of hemoglobinuria, hyperamylasemia, hyperglycemia, malignant hypertension, hepatospenomegaly, acute renal failure and hypertensive encephalopathy. One patient, who did not undergo reoperation, died due to multiple organ failure; the other one, who underwent operation revision in order to arrest the hemolysis, died of sepsis. Early reoperation was performed in the remaining patient to replace the double velour Dacron patch with a pericardium-covered knitted Dacron patch, and he survived. Hemolysis ceased in both patients who had the double velour Dacron patch replaced with a pericardium-covered patch. A review of the literature failed to show previous reports concerned with hemolysis associated with repair of a simple VSD. We now report what we believe to be the first cases in the literature with this unique clinical course following hemolysis.",
author = "H. Chang and Hung, {C. R.} and Huang, {F. Y.} and Wu, {G. J.}",
year = "1990",
month = "11",
language = "English",
volume = "89",
pages = "1004--1008",
journal = "Journal of the Formosan Medical Association",
issn = "0929-6646",
publisher = "Elsevier Science Publishers B.V.",
number = "11",

}

TY - JOUR

T1 - Hemolysis following correction of ventricular septal defect.

AU - Chang, H.

AU - Hung, C. R.

AU - Huang, F. Y.

AU - Wu, G. J.

PY - 1990/11

Y1 - 1990/11

N2 - Hemolysis following repair of a ventricular septal defect (VSD) is an unusual complication. Three cases of patients who had simple VSD are described here. After repair of the VSD, the postoperative course was complicated by the intravascular hemolysis induced by the interaction between the red blood cells and the double velour Dacron patch. Thus the patients' hemodynamic status deteriorated. The first 2 patients had a course of hemoglobinuria, hyperamylasemia, hyperglycemia, malignant hypertension, hepatospenomegaly, acute renal failure and hypertensive encephalopathy. One patient, who did not undergo reoperation, died due to multiple organ failure; the other one, who underwent operation revision in order to arrest the hemolysis, died of sepsis. Early reoperation was performed in the remaining patient to replace the double velour Dacron patch with a pericardium-covered knitted Dacron patch, and he survived. Hemolysis ceased in both patients who had the double velour Dacron patch replaced with a pericardium-covered patch. A review of the literature failed to show previous reports concerned with hemolysis associated with repair of a simple VSD. We now report what we believe to be the first cases in the literature with this unique clinical course following hemolysis.

AB - Hemolysis following repair of a ventricular septal defect (VSD) is an unusual complication. Three cases of patients who had simple VSD are described here. After repair of the VSD, the postoperative course was complicated by the intravascular hemolysis induced by the interaction between the red blood cells and the double velour Dacron patch. Thus the patients' hemodynamic status deteriorated. The first 2 patients had a course of hemoglobinuria, hyperamylasemia, hyperglycemia, malignant hypertension, hepatospenomegaly, acute renal failure and hypertensive encephalopathy. One patient, who did not undergo reoperation, died due to multiple organ failure; the other one, who underwent operation revision in order to arrest the hemolysis, died of sepsis. Early reoperation was performed in the remaining patient to replace the double velour Dacron patch with a pericardium-covered knitted Dacron patch, and he survived. Hemolysis ceased in both patients who had the double velour Dacron patch replaced with a pericardium-covered patch. A review of the literature failed to show previous reports concerned with hemolysis associated with repair of a simple VSD. We now report what we believe to be the first cases in the literature with this unique clinical course following hemolysis.

UR - http://www.scopus.com/inward/record.url?scp=0025522443&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025522443&partnerID=8YFLogxK

M3 - Article

VL - 89

SP - 1004

EP - 1008

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

SN - 0929-6646

IS - 11

ER -