Heart rate variability in Taiwanese obese children

Chen Chung Fu, Yin Ming Li, Dee Pei, Chien Lin Chen, Huey Ming Lo, Du An Wu, Terry B J Kuo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The primary purpose of the present community-based study was to investigate early changes in cardiac autonomic function in obese children. Materials and Methods: A survey of juvenile obesity in Hualien in eastern Taiwan was performed in 2002. A total of 1,724 adolescents who were 12 or 13 years old were recruited. The overall prevalences of normal weight, overweight and obese adolescents were 71.5% 13.1%, and 15.4%, respectively. A stratified random sampling scheme was performed. We selected 100, 50 and 75 subjects from the above-mentioned three groups, and invited them to join this study. Totally, 170 students (normal-weight: overweight: obese= 81: 34: 55) participated in this study. They received blood checks and a heart rate variability (HRV) examination. The homeostasis model assessment of insulin resistance (HOMA-IR) was used to evaluate insulin sensitivity. Results: Compared with the normal-weight group, the obese children had significantly elevated body mass indexes (BMI), HOMA-IR, and systolic and diastolic blood pressure levels. In addition, compared to their normal weight counterparts, obese children had significantly reduced high-frequency power (HF) but elevated low-frequency power in normalized units (LF %), and elevated ratios of low-frequency power to high-frequency power (LF/HF ratio). Further analyses revealed that compared with the normal weight counterparts; obese boys had significantly reduced HF but elevated LF % and LF/HF ratios. Among obese girls, the HF was reduced significantly, and LF% and the LF/HF ratio were increased, though not significantly. In stepwise multiple regression analysis, the BMI and heart rate were negatively associated with the HF component and positively associated with the LF/HF ratio and LF %. For every 1 kg/m2 increment in the BMI, the LF/HF ratio and LF % components of HRV increased ln(0.02) and 0.42% respectively, while HF decreased 0.03 ln(ms2). Boys had a higher LF/HF ratio and LF % than girls. Conclusions: The obese boys and girls had increased insulin resistance and changes in autonomic nervous function that included reduced parasympathetic control and obese boys had elevated sympathovagal modulation. Gender-related autonomic differences, such as girls having lower sympathetic modulations of HRV, were also noted.

Original languageEnglish
JournalTzu Chi Medical Journal
Volume18
Issue number3
Publication statusPublished - Jun 2006
Externally publishedYes

Fingerprint

Heart Rate
Insulin Resistance
Weights and Measures
Body Mass Index
Homeostasis
Blood Pressure
Taiwan
Obesity
Regression Analysis
Students

Keywords

  • Autonomic nerve dysfunction
  • Heart rate variability
  • Obese children

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fu, C. C., Li, Y. M., Pei, D., Chen, C. L., Lo, H. M., Wu, D. A., & Kuo, T. B. J. (2006). Heart rate variability in Taiwanese obese children. Tzu Chi Medical Journal, 18(3).

Heart rate variability in Taiwanese obese children. / Fu, Chen Chung; Li, Yin Ming; Pei, Dee; Chen, Chien Lin; Lo, Huey Ming; Wu, Du An; Kuo, Terry B J.

In: Tzu Chi Medical Journal, Vol. 18, No. 3, 06.2006.

Research output: Contribution to journalArticle

Fu, CC, Li, YM, Pei, D, Chen, CL, Lo, HM, Wu, DA & Kuo, TBJ 2006, 'Heart rate variability in Taiwanese obese children', Tzu Chi Medical Journal, vol. 18, no. 3.
Fu CC, Li YM, Pei D, Chen CL, Lo HM, Wu DA et al. Heart rate variability in Taiwanese obese children. Tzu Chi Medical Journal. 2006 Jun;18(3).
Fu, Chen Chung ; Li, Yin Ming ; Pei, Dee ; Chen, Chien Lin ; Lo, Huey Ming ; Wu, Du An ; Kuo, Terry B J. / Heart rate variability in Taiwanese obese children. In: Tzu Chi Medical Journal. 2006 ; Vol. 18, No. 3.
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