Health state utility, willingness to pay, and quality of life among Taiwanese patients with psoriasis

Wei Chih Ko, Tsen Fang Tsai, Chao Hsiun Tang

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background/Objective Past studies have found a correlation between the Dermatology Life Quality Index (DLQI) and the Psoriasis Area and Severity Index (PASI) for Caucasian psoriasis patients. This study examined the relationships between health state utility and willingness to pay (WTP) and the DLQI, as well as between the PASI and the DLQI, health-related utilities, and WTP in Taiwanese patients. Methods A total of 480 psoriasis patients from five hospitals across Taiwan were interviewed between August 2009 and February 2010. Health state utilities were elicited using the time trade-off (TTO) method, a visual analog scale (VAS), and the EuroQOL-five dimensions (EQ-5D). WTP for a cure was elicited by double-bounded binary-choice questions followed by a bidding game. Psoriasis severity was graded as mild (PASI < 3), moderate, or severe (PASI ≥ 10). Results The mean DLQI values for mild (n = 117), moderate (n = 208), and severe (n = 155) psoriasis were 5.73, 7.62, and 11.29, respectively. The mean health state utilities were 0.87 (EQ-5D), 0.72 (VAS), and 0.74 (TTO). The monthly maximum WTP value was US$145.3–318.8. EQ-5D and VAS scores were negatively correlated with all DLQI domains. WTP and DLQI also had a strong correlation in the expected direction. TTO had the weakest correlation with the DLQI. A smaller TTO was found for Taiwanese patients than for Caucasians. When considering different PASI severity levels, EQ-5D and VAS scores remained consistent measures for the DLQI, but the correlation between the TTO and DLQI weakened. Conclusion The EQ-5D, VAS, and WTP are consistent measures for the DLQI in assessing the well-being of psoriasis patients in Taiwan.

Original languageEnglish
Pages (from-to)185-191
Number of pages7
JournalDermatologica Sinica
Volume34
Issue number4
DOIs
Publication statusPublished - Dec 1 2016

Fingerprint

Dermatology
Psoriasis
Quality of Life
Health
Visual Analog Scale
Taiwan

Keywords

  • health state utility
  • psoriasis
  • Psoriasis Area and Severity Index
  • quality of life
  • time trade-off
  • willingness to pay

ASJC Scopus subject areas

  • Dermatology

Cite this

Health state utility, willingness to pay, and quality of life among Taiwanese patients with psoriasis. / Ko, Wei Chih; Tsai, Tsen Fang; Tang, Chao Hsiun.

In: Dermatologica Sinica, Vol. 34, No. 4, 01.12.2016, p. 185-191.

Research output: Contribution to journalArticle

@article{0a0ef4838c1d4ec49e87a506bd199db1,
title = "Health state utility, willingness to pay, and quality of life among Taiwanese patients with psoriasis",
abstract = "Background/Objective Past studies have found a correlation between the Dermatology Life Quality Index (DLQI) and the Psoriasis Area and Severity Index (PASI) for Caucasian psoriasis patients. This study examined the relationships between health state utility and willingness to pay (WTP) and the DLQI, as well as between the PASI and the DLQI, health-related utilities, and WTP in Taiwanese patients. Methods A total of 480 psoriasis patients from five hospitals across Taiwan were interviewed between August 2009 and February 2010. Health state utilities were elicited using the time trade-off (TTO) method, a visual analog scale (VAS), and the EuroQOL-five dimensions (EQ-5D). WTP for a cure was elicited by double-bounded binary-choice questions followed by a bidding game. Psoriasis severity was graded as mild (PASI < 3), moderate, or severe (PASI ≥ 10). Results The mean DLQI values for mild (n = 117), moderate (n = 208), and severe (n = 155) psoriasis were 5.73, 7.62, and 11.29, respectively. The mean health state utilities were 0.87 (EQ-5D), 0.72 (VAS), and 0.74 (TTO). The monthly maximum WTP value was US$145.3–318.8. EQ-5D and VAS scores were negatively correlated with all DLQI domains. WTP and DLQI also had a strong correlation in the expected direction. TTO had the weakest correlation with the DLQI. A smaller TTO was found for Taiwanese patients than for Caucasians. When considering different PASI severity levels, EQ-5D and VAS scores remained consistent measures for the DLQI, but the correlation between the TTO and DLQI weakened. Conclusion The EQ-5D, VAS, and WTP are consistent measures for the DLQI in assessing the well-being of psoriasis patients in Taiwan.",
keywords = "health state utility, psoriasis, Psoriasis Area and Severity Index, quality of life, time trade-off, willingness to pay",
author = "Ko, {Wei Chih} and Tsai, {Tsen Fang} and Tang, {Chao Hsiun}",
year = "2016",
month = "12",
day = "1",
doi = "10.1016/j.dsi.2016.05.004",
language = "English",
volume = "34",
pages = "185--191",
journal = "Dermatologica Sinica",
issn = "1027-8117",
publisher = "臺灣皮膚科醫學會",
number = "4",

}

TY - JOUR

T1 - Health state utility, willingness to pay, and quality of life among Taiwanese patients with psoriasis

AU - Ko, Wei Chih

AU - Tsai, Tsen Fang

AU - Tang, Chao Hsiun

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background/Objective Past studies have found a correlation between the Dermatology Life Quality Index (DLQI) and the Psoriasis Area and Severity Index (PASI) for Caucasian psoriasis patients. This study examined the relationships between health state utility and willingness to pay (WTP) and the DLQI, as well as between the PASI and the DLQI, health-related utilities, and WTP in Taiwanese patients. Methods A total of 480 psoriasis patients from five hospitals across Taiwan were interviewed between August 2009 and February 2010. Health state utilities were elicited using the time trade-off (TTO) method, a visual analog scale (VAS), and the EuroQOL-five dimensions (EQ-5D). WTP for a cure was elicited by double-bounded binary-choice questions followed by a bidding game. Psoriasis severity was graded as mild (PASI < 3), moderate, or severe (PASI ≥ 10). Results The mean DLQI values for mild (n = 117), moderate (n = 208), and severe (n = 155) psoriasis were 5.73, 7.62, and 11.29, respectively. The mean health state utilities were 0.87 (EQ-5D), 0.72 (VAS), and 0.74 (TTO). The monthly maximum WTP value was US$145.3–318.8. EQ-5D and VAS scores were negatively correlated with all DLQI domains. WTP and DLQI also had a strong correlation in the expected direction. TTO had the weakest correlation with the DLQI. A smaller TTO was found for Taiwanese patients than for Caucasians. When considering different PASI severity levels, EQ-5D and VAS scores remained consistent measures for the DLQI, but the correlation between the TTO and DLQI weakened. Conclusion The EQ-5D, VAS, and WTP are consistent measures for the DLQI in assessing the well-being of psoriasis patients in Taiwan.

AB - Background/Objective Past studies have found a correlation between the Dermatology Life Quality Index (DLQI) and the Psoriasis Area and Severity Index (PASI) for Caucasian psoriasis patients. This study examined the relationships between health state utility and willingness to pay (WTP) and the DLQI, as well as between the PASI and the DLQI, health-related utilities, and WTP in Taiwanese patients. Methods A total of 480 psoriasis patients from five hospitals across Taiwan were interviewed between August 2009 and February 2010. Health state utilities were elicited using the time trade-off (TTO) method, a visual analog scale (VAS), and the EuroQOL-five dimensions (EQ-5D). WTP for a cure was elicited by double-bounded binary-choice questions followed by a bidding game. Psoriasis severity was graded as mild (PASI < 3), moderate, or severe (PASI ≥ 10). Results The mean DLQI values for mild (n = 117), moderate (n = 208), and severe (n = 155) psoriasis were 5.73, 7.62, and 11.29, respectively. The mean health state utilities were 0.87 (EQ-5D), 0.72 (VAS), and 0.74 (TTO). The monthly maximum WTP value was US$145.3–318.8. EQ-5D and VAS scores were negatively correlated with all DLQI domains. WTP and DLQI also had a strong correlation in the expected direction. TTO had the weakest correlation with the DLQI. A smaller TTO was found for Taiwanese patients than for Caucasians. When considering different PASI severity levels, EQ-5D and VAS scores remained consistent measures for the DLQI, but the correlation between the TTO and DLQI weakened. Conclusion The EQ-5D, VAS, and WTP are consistent measures for the DLQI in assessing the well-being of psoriasis patients in Taiwan.

KW - health state utility

KW - psoriasis

KW - Psoriasis Area and Severity Index

KW - quality of life

KW - time trade-off

KW - willingness to pay

UR - http://www.scopus.com/inward/record.url?scp=84994850283&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84994850283&partnerID=8YFLogxK

U2 - 10.1016/j.dsi.2016.05.004

DO - 10.1016/j.dsi.2016.05.004

M3 - Article

VL - 34

SP - 185

EP - 191

JO - Dermatologica Sinica

JF - Dermatologica Sinica

SN - 1027-8117

IS - 4

ER -