Growth retardation as the initial manifestation of intracranial tumors

report of two cases.

J. S. Lee, W. Y. Tsai, H. M. Liu, M. Y. Lin, Y. K. Tu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Two boys (9 years and 14 years old) were brought to visit our pediatric endocrine clinic with the chief complaint of short stature. Because of growth retardation, they were admitted for further evaluation. Physical examinations, including neurological examinations, were unremarkable but the laboratory examination confirmed the diagnosis of hypopituitarism in both patients. Skull radiography examinations showed some calcifications at suprasellar regions in the case 1 but negative findings in case 2. Furthermore, computed tomography (CT) of the head of case 2 performed at an outside hospital half a year before was reported to be normal, so case 2 fits the conventional diagnosis of idiopathic hypopituitarism. However, magnetic resonance image (MRI) study of the head disclosed that both of them are victims of an intracranial tumor, craniopharyngioma and germ cell tumors respectively. After surgical intervention, followed by radiotherapy, both patients were stable without any neurological deficit. Our experience confirmed that an MRI study of sellar region is warranted in search of the etiology of hypopituitarism.

Original languageEnglish
Pages (from-to)157-162
Number of pages6
JournalActa Paediatrica Sinica
Volume35
Issue number2
Publication statusPublished - Mar 1 1994
Externally publishedYes

Fingerprint

Hypopituitarism
Magnetic Resonance Spectroscopy
Growth
Head
Craniopharyngioma
Neoplasms
Clinical Laboratory Techniques
Germ Cell and Embryonal Neoplasms
Neurologic Examination
Skull
Radiography
Physical Examination
Radiotherapy
Tomography
Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Growth retardation as the initial manifestation of intracranial tumors : report of two cases. / Lee, J. S.; Tsai, W. Y.; Liu, H. M.; Lin, M. Y.; Tu, Y. K.

In: Acta Paediatrica Sinica, Vol. 35, No. 2, 01.03.1994, p. 157-162.

Research output: Contribution to journalArticle

Lee, J. S. ; Tsai, W. Y. ; Liu, H. M. ; Lin, M. Y. ; Tu, Y. K. / Growth retardation as the initial manifestation of intracranial tumors : report of two cases. In: Acta Paediatrica Sinica. 1994 ; Vol. 35, No. 2. pp. 157-162.
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