Granulomatous balanitis as an unusual complication after intravesical bacillus Calmette-Guerin therapy for bladder cancer

D. S. Yu, S. Y. Chang, T. H. Yang, H. J. Harn, W. H. Lee, C. P. Ma

Research output: Contribution to journalArticle

Abstract

Intravesical bacillus Calmette-Guerin (BCG) instillation is a well-established therapy for superficial bladder cancer. Urinary tract and systemic complications induced by BCG instillation have been reported by various investigators. To date, BCG-induced granulomatous balanitis has been reported only twice. Herein, we report a male patient who underwent 100 mg of Taipei-NIPM BCG intravesical instillation weekly for six consecutive doses as treatment for recurrent and chemotherapeutic-resistant superficial bladder cancer, and, two months later, developed granulomatous balanitis. The patient initially presented symptoms of anterior urethral pain and weakness of stream with progressive bullous changes over the glans penis. Granulomatous balanitis was diagnosed after an excisional biopsy was performed during the first follow-up cystoscopic examination. After three months with isoniazid treatment, these lesions totally subsided without any sequelae.

Original languageEnglish
Pages (from-to)246-248
Number of pages3
JournalAsian Journal of Surgery
Volume19
Issue number3
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Balanitis
Mycobacterium bovis
Urinary Bladder Neoplasms
Intravesical Administration
Penis
Isoniazid
Therapeutics
Urinary Tract
Research Personnel
Biopsy
Pain

ASJC Scopus subject areas

  • Surgery

Cite this

Granulomatous balanitis as an unusual complication after intravesical bacillus Calmette-Guerin therapy for bladder cancer. / Yu, D. S.; Chang, S. Y.; Yang, T. H.; Harn, H. J.; Lee, W. H.; Ma, C. P.

In: Asian Journal of Surgery, Vol. 19, No. 3, 1996, p. 246-248.

Research output: Contribution to journalArticle

Yu, D. S. ; Chang, S. Y. ; Yang, T. H. ; Harn, H. J. ; Lee, W. H. ; Ma, C. P. / Granulomatous balanitis as an unusual complication after intravesical bacillus Calmette-Guerin therapy for bladder cancer. In: Asian Journal of Surgery. 1996 ; Vol. 19, No. 3. pp. 246-248.
@article{25f3feb7998841f284345b95ae6ebda8,
title = "Granulomatous balanitis as an unusual complication after intravesical bacillus Calmette-Guerin therapy for bladder cancer",
abstract = "Intravesical bacillus Calmette-Guerin (BCG) instillation is a well-established therapy for superficial bladder cancer. Urinary tract and systemic complications induced by BCG instillation have been reported by various investigators. To date, BCG-induced granulomatous balanitis has been reported only twice. Herein, we report a male patient who underwent 100 mg of Taipei-NIPM BCG intravesical instillation weekly for six consecutive doses as treatment for recurrent and chemotherapeutic-resistant superficial bladder cancer, and, two months later, developed granulomatous balanitis. The patient initially presented symptoms of anterior urethral pain and weakness of stream with progressive bullous changes over the glans penis. Granulomatous balanitis was diagnosed after an excisional biopsy was performed during the first follow-up cystoscopic examination. After three months with isoniazid treatment, these lesions totally subsided without any sequelae.",
author = "Yu, {D. S.} and Chang, {S. Y.} and Yang, {T. H.} and Harn, {H. J.} and Lee, {W. H.} and Ma, {C. P.}",
year = "1996",
language = "English",
volume = "19",
pages = "246--248",
journal = "Asian Journal of Surgery",
issn = "1015-9584",
publisher = "Elsevier Taiwan LLC",
number = "3",

}

TY - JOUR

T1 - Granulomatous balanitis as an unusual complication after intravesical bacillus Calmette-Guerin therapy for bladder cancer

AU - Yu, D. S.

AU - Chang, S. Y.

AU - Yang, T. H.

AU - Harn, H. J.

AU - Lee, W. H.

AU - Ma, C. P.

PY - 1996

Y1 - 1996

N2 - Intravesical bacillus Calmette-Guerin (BCG) instillation is a well-established therapy for superficial bladder cancer. Urinary tract and systemic complications induced by BCG instillation have been reported by various investigators. To date, BCG-induced granulomatous balanitis has been reported only twice. Herein, we report a male patient who underwent 100 mg of Taipei-NIPM BCG intravesical instillation weekly for six consecutive doses as treatment for recurrent and chemotherapeutic-resistant superficial bladder cancer, and, two months later, developed granulomatous balanitis. The patient initially presented symptoms of anterior urethral pain and weakness of stream with progressive bullous changes over the glans penis. Granulomatous balanitis was diagnosed after an excisional biopsy was performed during the first follow-up cystoscopic examination. After three months with isoniazid treatment, these lesions totally subsided without any sequelae.

AB - Intravesical bacillus Calmette-Guerin (BCG) instillation is a well-established therapy for superficial bladder cancer. Urinary tract and systemic complications induced by BCG instillation have been reported by various investigators. To date, BCG-induced granulomatous balanitis has been reported only twice. Herein, we report a male patient who underwent 100 mg of Taipei-NIPM BCG intravesical instillation weekly for six consecutive doses as treatment for recurrent and chemotherapeutic-resistant superficial bladder cancer, and, two months later, developed granulomatous balanitis. The patient initially presented symptoms of anterior urethral pain and weakness of stream with progressive bullous changes over the glans penis. Granulomatous balanitis was diagnosed after an excisional biopsy was performed during the first follow-up cystoscopic examination. After three months with isoniazid treatment, these lesions totally subsided without any sequelae.

UR - http://www.scopus.com/inward/record.url?scp=0029810569&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029810569&partnerID=8YFLogxK

M3 - Article

VL - 19

SP - 246

EP - 248

JO - Asian Journal of Surgery

JF - Asian Journal of Surgery

SN - 1015-9584

IS - 3

ER -