Global cost modeling analysis of HIV-1 and HCV viral load assays

Tarek Elbeik, Ralph Dalessandro, Yi Ming Arthur Chen, Serguei V. Soutchkov, Richard A. Loftus, Scott Beringer

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

This review addresses hidden costs associated with the Bayer VERSANT® assay, Roche AMPLICOR MONITOR® test and COBAS AMPLICOR MONITOR® test and how these influence the final per reportable cost to a testing laboratory in resource-rich and -poor countries. An in-depth evaluation and recommendation of the most cost-effective approach for these tests is presented. The analyses demonstrate the need for manufacturers to consider labor and supply costs when marketing a kit in resource-poor countries, noting that marketing strategies need to change. In the absence of any proven monitoring alternative, emphasis is placed on increasing market share to promote significant reduction in kit prices to suit the demands of markets in resource-poor countries. Finally, recommendations are made to improve the overall cost structure of viral load testing. This review is intended as a tool to optimize assay usage in attaining the lowest performance costs by assay and is not to endorse any test, as will become apparent.

Original languageEnglish
Pages (from-to)383-407
Number of pages25
JournalExpert Review of Pharmacoeconomics and Outcomes Research
Volume3
Issue number4
DOIs
Publication statusPublished - Aug 1 2003
Externally publishedYes

Fingerprint

Viral Load
HIV-1
Costs and Cost Analysis
Marketing

Keywords

  • Bayer VERSANT bDNA
  • Center of excellence
  • COBAS
  • Cost model
  • Examples
  • HCV
  • HIV-1
  • Labor and supply costs
  • Resource-poor countries
  • Resource-rich countries
  • Roche AMPLICOR MONITOR

ASJC Scopus subject areas

  • Health Policy
  • Pharmacology (medical)

Cite this

Global cost modeling analysis of HIV-1 and HCV viral load assays. / Elbeik, Tarek; Dalessandro, Ralph; Chen, Yi Ming Arthur; Soutchkov, Serguei V.; Loftus, Richard A.; Beringer, Scott.

In: Expert Review of Pharmacoeconomics and Outcomes Research, Vol. 3, No. 4, 01.08.2003, p. 383-407.

Research output: Contribution to journalReview article

Elbeik, Tarek ; Dalessandro, Ralph ; Chen, Yi Ming Arthur ; Soutchkov, Serguei V. ; Loftus, Richard A. ; Beringer, Scott. / Global cost modeling analysis of HIV-1 and HCV viral load assays. In: Expert Review of Pharmacoeconomics and Outcomes Research. 2003 ; Vol. 3, No. 4. pp. 383-407.
@article{b382be2c595741d98ae2c64d1ac91605,
title = "Global cost modeling analysis of HIV-1 and HCV viral load assays",
abstract = "This review addresses hidden costs associated with the Bayer VERSANT{\circledR} assay, Roche AMPLICOR MONITOR{\circledR} test and COBAS AMPLICOR MONITOR{\circledR} test and how these influence the final per reportable cost to a testing laboratory in resource-rich and -poor countries. An in-depth evaluation and recommendation of the most cost-effective approach for these tests is presented. The analyses demonstrate the need for manufacturers to consider labor and supply costs when marketing a kit in resource-poor countries, noting that marketing strategies need to change. In the absence of any proven monitoring alternative, emphasis is placed on increasing market share to promote significant reduction in kit prices to suit the demands of markets in resource-poor countries. Finally, recommendations are made to improve the overall cost structure of viral load testing. This review is intended as a tool to optimize assay usage in attaining the lowest performance costs by assay and is not to endorse any test, as will become apparent.",
keywords = "Bayer VERSANT bDNA, Center of excellence, COBAS, Cost model, Examples, HCV, HIV-1, Labor and supply costs, Resource-poor countries, Resource-rich countries, Roche AMPLICOR MONITOR",
author = "Tarek Elbeik and Ralph Dalessandro and Chen, {Yi Ming Arthur} and Soutchkov, {Serguei V.} and Loftus, {Richard A.} and Scott Beringer",
year = "2003",
month = "8",
day = "1",
doi = "10.1586/14737167.3.4.383",
language = "English",
volume = "3",
pages = "383--407",
journal = "Expert Review of Pharmacoeconomics and Outcomes Research",
issn = "1473-7167",
publisher = "Expert Reviews Ltd.",
number = "4",

}

TY - JOUR

T1 - Global cost modeling analysis of HIV-1 and HCV viral load assays

AU - Elbeik, Tarek

AU - Dalessandro, Ralph

AU - Chen, Yi Ming Arthur

AU - Soutchkov, Serguei V.

AU - Loftus, Richard A.

AU - Beringer, Scott

PY - 2003/8/1

Y1 - 2003/8/1

N2 - This review addresses hidden costs associated with the Bayer VERSANT® assay, Roche AMPLICOR MONITOR® test and COBAS AMPLICOR MONITOR® test and how these influence the final per reportable cost to a testing laboratory in resource-rich and -poor countries. An in-depth evaluation and recommendation of the most cost-effective approach for these tests is presented. The analyses demonstrate the need for manufacturers to consider labor and supply costs when marketing a kit in resource-poor countries, noting that marketing strategies need to change. In the absence of any proven monitoring alternative, emphasis is placed on increasing market share to promote significant reduction in kit prices to suit the demands of markets in resource-poor countries. Finally, recommendations are made to improve the overall cost structure of viral load testing. This review is intended as a tool to optimize assay usage in attaining the lowest performance costs by assay and is not to endorse any test, as will become apparent.

AB - This review addresses hidden costs associated with the Bayer VERSANT® assay, Roche AMPLICOR MONITOR® test and COBAS AMPLICOR MONITOR® test and how these influence the final per reportable cost to a testing laboratory in resource-rich and -poor countries. An in-depth evaluation and recommendation of the most cost-effective approach for these tests is presented. The analyses demonstrate the need for manufacturers to consider labor and supply costs when marketing a kit in resource-poor countries, noting that marketing strategies need to change. In the absence of any proven monitoring alternative, emphasis is placed on increasing market share to promote significant reduction in kit prices to suit the demands of markets in resource-poor countries. Finally, recommendations are made to improve the overall cost structure of viral load testing. This review is intended as a tool to optimize assay usage in attaining the lowest performance costs by assay and is not to endorse any test, as will become apparent.

KW - Bayer VERSANT bDNA

KW - Center of excellence

KW - COBAS

KW - Cost model

KW - Examples

KW - HCV

KW - HIV-1

KW - Labor and supply costs

KW - Resource-poor countries

KW - Resource-rich countries

KW - Roche AMPLICOR MONITOR

UR - http://www.scopus.com/inward/record.url?scp=0041560004&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0041560004&partnerID=8YFLogxK

U2 - 10.1586/14737167.3.4.383

DO - 10.1586/14737167.3.4.383

M3 - Review article

VL - 3

SP - 383

EP - 407

JO - Expert Review of Pharmacoeconomics and Outcomes Research

JF - Expert Review of Pharmacoeconomics and Outcomes Research

SN - 1473-7167

IS - 4

ER -