Giant intracranial mesenchymal chondrosarcoma with uncal herniation

Hung Shih Lin, Cheng Chia Tsai, Cheng Kuei Chang, Shiu Jau Chen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Mesenchymal chondrosarcomas are very rare central nervous system (CNS) tumors consisting of undifferentiated mesenchymal cells plus islets of cartilage. We report a case of giant intracranial mesenchymal chondrosarcomas presenting with acute neurologic deterioration. A 22-year-old woman presented with right facial and hand numbness and ocular torsion for about 2 weeks. Magnetic resonance imaging (MRI) disclosed a mass in the right middle cranial fossa with a mass effect. Two days before scheduled surgery, the patient suddenly lost consciousness and was found to have uncal herniation. At emergency surgery, the tumor was totally excised. Pathologically, there was a dimorphic pattern of undifferentiated cells and islets of cartilage, consistent with mesenchymal chondrosarcoma. Although the patient survived surgery, she remained in a vegetative state. The tumor recurred 3 years after surgery. Intracranial mesenchymal chondrosarcoma is rare and should be considered when evaluating a tumor with dural involvement, particularly in younger adults. Differential diagnoses include intracranial meningioma and schwannoma. An aggressive surgical resection is highly recommended because of the high risk of recurrence.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalFormosan Journal of Surgery
Volume45
Issue number3
DOIs
Publication statusPublished - Jun 2012

Fingerprint

Mesenchymal Chondrosarcoma
Islets of Langerhans
Cartilage
Middle Cranial Fossa
Persistent Vegetative State
Central Nervous System Neoplasms
Neoplasms
Hypesthesia
Neurilemmoma
Meningioma
Consciousness
Nervous System
Young Adult
Emergencies
Differential Diagnosis
Hand
Magnetic Resonance Imaging
Recurrence

Keywords

  • Intracranial neoplasm
  • Intracranial tumors
  • Mesenchymal chondrosarcoma
  • Surgery

ASJC Scopus subject areas

  • Surgery

Cite this

Giant intracranial mesenchymal chondrosarcoma with uncal herniation. / Lin, Hung Shih; Tsai, Cheng Chia; Chang, Cheng Kuei; Chen, Shiu Jau.

In: Formosan Journal of Surgery, Vol. 45, No. 3, 06.2012, p. 93-96.

Research output: Contribution to journalArticle

Lin, Hung Shih ; Tsai, Cheng Chia ; Chang, Cheng Kuei ; Chen, Shiu Jau. / Giant intracranial mesenchymal chondrosarcoma with uncal herniation. In: Formosan Journal of Surgery. 2012 ; Vol. 45, No. 3. pp. 93-96.
@article{0594d85bac7644d685a06bcb45ba2bb0,
title = "Giant intracranial mesenchymal chondrosarcoma with uncal herniation",
abstract = "Mesenchymal chondrosarcomas are very rare central nervous system (CNS) tumors consisting of undifferentiated mesenchymal cells plus islets of cartilage. We report a case of giant intracranial mesenchymal chondrosarcomas presenting with acute neurologic deterioration. A 22-year-old woman presented with right facial and hand numbness and ocular torsion for about 2 weeks. Magnetic resonance imaging (MRI) disclosed a mass in the right middle cranial fossa with a mass effect. Two days before scheduled surgery, the patient suddenly lost consciousness and was found to have uncal herniation. At emergency surgery, the tumor was totally excised. Pathologically, there was a dimorphic pattern of undifferentiated cells and islets of cartilage, consistent with mesenchymal chondrosarcoma. Although the patient survived surgery, she remained in a vegetative state. The tumor recurred 3 years after surgery. Intracranial mesenchymal chondrosarcoma is rare and should be considered when evaluating a tumor with dural involvement, particularly in younger adults. Differential diagnoses include intracranial meningioma and schwannoma. An aggressive surgical resection is highly recommended because of the high risk of recurrence.",
keywords = "Intracranial neoplasm, Intracranial tumors, Mesenchymal chondrosarcoma, Surgery",
author = "Lin, {Hung Shih} and Tsai, {Cheng Chia} and Chang, {Cheng Kuei} and Chen, {Shiu Jau}",
year = "2012",
month = "6",
doi = "10.1016/j.fjs.2012.01.004",
language = "English",
volume = "45",
pages = "93--96",
journal = "Formosan Journal of Surgery",
issn = "1011-6788",
publisher = "臺灣外科醫學會",
number = "3",

}

TY - JOUR

T1 - Giant intracranial mesenchymal chondrosarcoma with uncal herniation

AU - Lin, Hung Shih

AU - Tsai, Cheng Chia

AU - Chang, Cheng Kuei

AU - Chen, Shiu Jau

PY - 2012/6

Y1 - 2012/6

N2 - Mesenchymal chondrosarcomas are very rare central nervous system (CNS) tumors consisting of undifferentiated mesenchymal cells plus islets of cartilage. We report a case of giant intracranial mesenchymal chondrosarcomas presenting with acute neurologic deterioration. A 22-year-old woman presented with right facial and hand numbness and ocular torsion for about 2 weeks. Magnetic resonance imaging (MRI) disclosed a mass in the right middle cranial fossa with a mass effect. Two days before scheduled surgery, the patient suddenly lost consciousness and was found to have uncal herniation. At emergency surgery, the tumor was totally excised. Pathologically, there was a dimorphic pattern of undifferentiated cells and islets of cartilage, consistent with mesenchymal chondrosarcoma. Although the patient survived surgery, she remained in a vegetative state. The tumor recurred 3 years after surgery. Intracranial mesenchymal chondrosarcoma is rare and should be considered when evaluating a tumor with dural involvement, particularly in younger adults. Differential diagnoses include intracranial meningioma and schwannoma. An aggressive surgical resection is highly recommended because of the high risk of recurrence.

AB - Mesenchymal chondrosarcomas are very rare central nervous system (CNS) tumors consisting of undifferentiated mesenchymal cells plus islets of cartilage. We report a case of giant intracranial mesenchymal chondrosarcomas presenting with acute neurologic deterioration. A 22-year-old woman presented with right facial and hand numbness and ocular torsion for about 2 weeks. Magnetic resonance imaging (MRI) disclosed a mass in the right middle cranial fossa with a mass effect. Two days before scheduled surgery, the patient suddenly lost consciousness and was found to have uncal herniation. At emergency surgery, the tumor was totally excised. Pathologically, there was a dimorphic pattern of undifferentiated cells and islets of cartilage, consistent with mesenchymal chondrosarcoma. Although the patient survived surgery, she remained in a vegetative state. The tumor recurred 3 years after surgery. Intracranial mesenchymal chondrosarcoma is rare and should be considered when evaluating a tumor with dural involvement, particularly in younger adults. Differential diagnoses include intracranial meningioma and schwannoma. An aggressive surgical resection is highly recommended because of the high risk of recurrence.

KW - Intracranial neoplasm

KW - Intracranial tumors

KW - Mesenchymal chondrosarcoma

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=84863102595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863102595&partnerID=8YFLogxK

U2 - 10.1016/j.fjs.2012.01.004

DO - 10.1016/j.fjs.2012.01.004

M3 - Article

VL - 45

SP - 93

EP - 96

JO - Formosan Journal of Surgery

JF - Formosan Journal of Surgery

SN - 1011-6788

IS - 3

ER -