Abstract
North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained from the public domain, it was classified as genome type 1-B; it is phylogenetically related to the predominant EV-D68 viruses that circulated in 2009 in Vietnam. It is necessary to strengthen EV-D68 detection globally, including in children with acute liver failure. Moreover, harmonization of genomic analysis of EV-D68 is desirable to understand global evolution of EV-D68.
| Original language | English |
|---|---|
| Journal | Journal of the Formosan Medical Association |
| DOIs | |
| Publication status | Accepted/In press - Jan 1 2018 |
| Externally published | Yes |
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Keywords
- Enterovirus D68
- Genome study
- Molecular epidemiology
- Next-generation sequencing
ASJC Scopus subject areas
- Medicine(all)
Cite this
Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan. / Chien, Yeh Sheng; Luo, Shu Ting; Tsao, Kuo Chien; Wang, Ying Hsiang; Lin, Tzou-Yien; Huang, Yhu Chering; Lee, Min Shi.
In: Journal of the Formosan Medical Association, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan
AU - Chien, Yeh Sheng
AU - Luo, Shu Ting
AU - Tsao, Kuo Chien
AU - Wang, Ying Hsiang
AU - Lin, Tzou-Yien
AU - Huang, Yhu Chering
AU - Lee, Min Shi
PY - 2018/1/1
Y1 - 2018/1/1
N2 - North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained from the public domain, it was classified as genome type 1-B; it is phylogenetically related to the predominant EV-D68 viruses that circulated in 2009 in Vietnam. It is necessary to strengthen EV-D68 detection globally, including in children with acute liver failure. Moreover, harmonization of genomic analysis of EV-D68 is desirable to understand global evolution of EV-D68.
AB - North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained from the public domain, it was classified as genome type 1-B; it is phylogenetically related to the predominant EV-D68 viruses that circulated in 2009 in Vietnam. It is necessary to strengthen EV-D68 detection globally, including in children with acute liver failure. Moreover, harmonization of genomic analysis of EV-D68 is desirable to understand global evolution of EV-D68.
KW - Enterovirus D68
KW - Genome study
KW - Molecular epidemiology
KW - Next-generation sequencing
UR - http://www.scopus.com/inward/record.url?scp=85055044590&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055044590&partnerID=8YFLogxK
U2 - 10.1016/j.jfma.2018.09.021
DO - 10.1016/j.jfma.2018.09.021
M3 - Article
C2 - 30342725
AN - SCOPUS:85055044590
JO - Journal of the Formosan Medical Association
JF - Journal of the Formosan Medical Association
SN - 0929-6646
ER -