Genomic analysis of enterovirus D68, including one strain isolated from a child with Wilson's disease in Taiwan

Yeh Sheng Chien, Shu Ting Luo, Kuo Chien Tsao, Ying Hsiang Wang, Tzou-Yien Lin, Yhu Chering Huang, Min Shi Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

North America experienced life-threatening outbreaks of enterovirus D68 (EV-D68) in 2014. We retrospectively detected EV-D68 from a child with Wilson's disease in 2008 in Taiwan. After comparing this EV-D68/Taiwan/2008 strain with EV-D68 genomes obtained from the public domain, it was classified as genome type 1-B; it is phylogenetically related to the predominant EV-D68 viruses that circulated in 2009 in Vietnam. It is necessary to strengthen EV-D68 detection globally, including in children with acute liver failure. Moreover, harmonization of genomic analysis of EV-D68 is desirable to understand global evolution of EV-D68.

Original languageEnglish
JournalJournal of the Formosan Medical Association
DOIs
Publication statusAccepted/In press - Jan 1 2018
Externally publishedYes

Keywords

  • Enterovirus D68
  • Genome study
  • Molecular epidemiology
  • Next-generation sequencing

ASJC Scopus subject areas

  • Medicine(all)

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