Breast cancer is the most common cancer in women in the world. According to the most recent estimates from GLOBOCAN published by the International Agency for Research on Cancer (IARC) , there were nearly 1.7 million new breast cancer cases diagnosed in 2012(25.2% of all cancers in women) and 6.3 millions have been diagnosed with breast cancer in 2007-2012. Breast cancer incidence has been increasing by more than 20% and mortality increased by 14% since 2008 and is the most common cause of cancer death in women in less developed regions (324,000 deaths, 14.3% of total). Breast cancer is less favorable in the underdeveloped countries due to less advanced medical diagnosis and treatments. Therefore a good diagnosis/prognosis would help to prevent as well as provide effective clinical treatments.
Hsu, M-T. (2015). Genome-Wide Gene Expression Analysis to Identify Epistatic Gene-Pairs Associated with Prognosis of Breast Cancer. In A Concise Review of Molecular Pathology of Breast Cancer (pp. 57-78). InTech. https://doi.org/10.5772/59462