Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 65-75 |
| Number of pages | 11 |
| Journal | 放射治療與腫瘤學 |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2013 |
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Keywords
- 大腸直腸癌
- 基因定序
- 立體定位放射線治療
- 化學治療
- Colorectal carcinoma
- Gene sequence
- SBRT (Stereotactic Body Radiation Therapy)
- Chemotherapy
Cite this
Gene Sequencing for Selection of Chemotherapy Drugs Combined with Stereotactic Body Radiation Therapy for Stage IV Colon Cancer: A Case Report. / 黃姚儒(Yao-Ru Huang); 陳尚文; 丁禮莉(Lai-Lei Ting); 郭嘉駿(Chia-Chun Kuo); 邱仲峰.
In: 放射治療與腫瘤學, Vol. 20, No. 1, 2013, p. 65-75.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gene Sequencing for Selection of Chemotherapy Drugs Combined with Stereotactic Body Radiation Therapy for Stage IV Colon Cancer: A Case Report
AU - 黃, 姚儒(Yao-Ru Huang)
AU - 陳, 尚文
AU - 丁, 禮莉(Lai-Lei Ting)
AU - 郭, 嘉駿(Chia-Chun Kuo)
AU - 邱, 仲峰
PY - 2013
Y1 - 2013
N2 - Gene sequencing may be a feasible means of individualizing cancer treatment. By investigating the correlation between genetic profiles and treatment outcomes of chemotherapy, it may be possible to determine effective treatment strategies according to individual genotypes in cancer patients. Despite great advances in drugs for cancer treatment, treatment outcomes may be improved by analyzing genetic markers that indicate treatment efficacy. We report the treatment for a patient with metastatic colon cancer in which gene sequencing was used for the selection of an effective chemotherapy regimen. In addition, we describe the entire course of treatment, including the combination of surgical resection for local control and radiotherapy to eradicate distant metastases. This is a pilot report of the clinical use of gene sequencing for determining a treatment regimen. Further clinical trials are needed to optimize the personalization of cancer treatment.
AB - Gene sequencing may be a feasible means of individualizing cancer treatment. By investigating the correlation between genetic profiles and treatment outcomes of chemotherapy, it may be possible to determine effective treatment strategies according to individual genotypes in cancer patients. Despite great advances in drugs for cancer treatment, treatment outcomes may be improved by analyzing genetic markers that indicate treatment efficacy. We report the treatment for a patient with metastatic colon cancer in which gene sequencing was used for the selection of an effective chemotherapy regimen. In addition, we describe the entire course of treatment, including the combination of surgical resection for local control and radiotherapy to eradicate distant metastases. This is a pilot report of the clinical use of gene sequencing for determining a treatment regimen. Further clinical trials are needed to optimize the personalization of cancer treatment.
KW - 大腸直腸癌
KW - 基因定序
KW - 立體定位放射線治療
KW - 化學治療
KW - Colorectal carcinoma
KW - Gene sequence
KW - SBRT (Stereotactic Body Radiation Therapy)
KW - Chemotherapy
KW - Colorectal carcinoma
KW - Gene sequence
KW - SBRT (Stereotactic Body Radiation Therapy)
KW - Chemotherapy
UR - http://www.airitilibrary.com/Publication/alDetailedMesh?DocID=1023988x-201303-201304250003-201304250003-65-75
U2 - 10.6316/TRO/201320(1)65
DO - 10.6316/TRO/201320(1)65
M3 - Article
VL - 20
SP - 65
EP - 75
JO - 放射治療與腫瘤學
JF - 放射治療與腫瘤學
SN - 1023-988x
IS - 1
ER -