GATA-2 Transduces LPS-Induced il-1β Gene Expression in Macrophages via a Toll-Like Receptor 4/MD88/MAPK-Dependent Mechanism

Agriculture & Biology

• Toll-like receptor 4 100%
• mitogen-activated protein kinase 71%
• lipopolysaccharides 63%
• macrophages 59%
• gene expression 40%
• interleukin-1 34%
• small interfering RNA 25%
• protein synthesis 16%
• transcriptional activation 16%
• transfection 16%
• primary contact 12%
• mitogen-activated protein kinase kinase 10%
• RNA interference 7%
• bioinformatics 7%
• phosphorylation 6%
• translation (genetics) 6%
• lungs 5%
• transcription factors 5%
• cytoplasm 5%
• promoter regions 5%
• cells 4%
• genes 2%

Medicine & Life Sciences

• Toll-Like Receptor 4 76%
• Mitogen-Activated Protein Kinases 65%
• Lipopolysaccharides 56%
• Macrophages 46%
• Gene Expression 39%
• Interleukin-1 29%
• Messenger RNA 21%
• Small Interfering RNA 18%
• Transcriptional Activation 13%
• GATA2 Transcription Factor 12%
• Transfection 12%
• MAP Kinase Kinase 2 11%
• MAP Kinase Kinase 1 11%
• RAW 264.7 Cells 9%
• Acute Lung Injury 8%
• Proteins 8%
• Genetic Promoter Regions 7%
• RNA Interference 7%
• Computational Biology 6%
• Cytoplasm 6%
• Phosphorylation 5%
• Genes 2%

Chemical Compounds

• Lipopolysaccharide 60%
• Silencing RNA 28%
• Protein 27%
• Small Interfering RNA 15%
• Cell Activity 15%