Gastrointestinal amyloidosis in a patient with systemic sclerosis

Yu Hsiang Chiu, Peng Jen Chen, Yi Ming Chang, Tsung Yun Hou

Research output: Contribution to journalArticle

Abstract

There were more than 90% of systemic sclerosis (SSc) patients developing gastrointestinal tract involvement with affecting esophagus mostly. However, a typical gastrointestinal manifestation may be not the only result of SSc. We described a 70-year-old female with SSc presented poor appetite, intermittent heartburn sensation, nausea, frequent sensation of abdominal fullness, and intermittent dull pain for 2 months. The esophagogastroduodenoscopy showed gastrointestinal as gastroesophageal reflux disease. The biopsy revealed amorphous material deposited in the vascular walls and apple-green birefringence in a polarization examination with Congo red staining which proved amyloidosis. The SSc patient with gastrointestinal involvement suggests to receive esophagogastroduodenoscopy, and a biopsy may be helpful to these patients to examine the possibility of secondary amyloidosis. These patients need more aggressively disease activity control.

Original languageEnglish
Pages (from-to)117-119
Number of pages3
JournalJournal of Medical Sciences (Taiwan)
Volume37
Issue number3
DOIs
Publication statusPublished - Jan 1 2017
Externally publishedYes

Fingerprint

Systemic Scleroderma
Amyloidosis
Digestive System Endoscopy
Birefringence
Biopsy
Congo Red
Heartburn
Appetite
Gastroesophageal Reflux
Nausea
Esophagus
Blood Vessels
Gastrointestinal Tract
Staining and Labeling
Pain

Keywords

  • Amyloidosis
  • Gastroesophageal reflux disease
  • Systemic sclerosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gastrointestinal amyloidosis in a patient with systemic sclerosis. / Chiu, Yu Hsiang; Chen, Peng Jen; Chang, Yi Ming; Hou, Tsung Yun.

In: Journal of Medical Sciences (Taiwan), Vol. 37, No. 3, 01.01.2017, p. 117-119.

Research output: Contribution to journalArticle

Chiu, Yu Hsiang ; Chen, Peng Jen ; Chang, Yi Ming ; Hou, Tsung Yun. / Gastrointestinal amyloidosis in a patient with systemic sclerosis. In: Journal of Medical Sciences (Taiwan). 2017 ; Vol. 37, No. 3. pp. 117-119.
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