Gastric leiomyosarcoma: A clinicopathological review

S. M. Sheen-Chen, F. F. Chou, H. L. Eng, J. J. Chen, C. M. Lee, Y. L. Wan

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: To report our experience of eight patients with primary gastric leiomyosarcoma. Design: Retrospective study. Setting: Teaching hospital, Taiwan. Subjects: 8 patients who presented with primary gastric leiomyosarcoma between 1986 and 1990. Main outcome measures: Endoscopic, radiological, and histopathological features, DNA ploidy, and outcome. Results: Abdominal pain and gastrointestinal bleeding were the most common presenting symptoms. In 5 of the 7 patients who had endoscopy preoperatively a diagnosis of submucosal tumour was made, but a definite diagnosis of leiomyosarcoma was made in only 3. A provisional diagnosis of leiomyosarcoma was made in 3 of the 4 patients who had computed tomography. All patients underwent some form of gastric resection ranging from palliative resection to total gastrectomy. Patients in whom the tumour had invaded adjacent organs had a poor prognosis. Histopathological grading of tumours correlated well with DNA ploidy. Conclusion: Both histopathological grading and DNA ploidy could be helpful objective prognostic criteria in patients with primary gastric leiomyosarcoma.

Original languageEnglish
Pages (from-to)681-687
Number of pages7
JournalEuropean Journal of Surgery, Acta Chirurgica
Volume160
Issue number12
Publication statusPublished - Jan 1 1994
Externally publishedYes

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Leiomyosarcoma
Stomach
Ploidies
DNA
Neoplasm Grading
Gastrectomy
Taiwan
Teaching Hospitals
Abdominal Pain
Endoscopy
Neoplasms
Retrospective Studies
Tomography
Outcome Assessment (Health Care)
Hemorrhage

Keywords

  • DNA ploidy
  • Gastric leiomyosarcoma

ASJC Scopus subject areas

  • Surgery

Cite this

Sheen-Chen, S. M., Chou, F. F., Eng, H. L., Chen, J. J., Lee, C. M., & Wan, Y. L. (1994). Gastric leiomyosarcoma: A clinicopathological review. European Journal of Surgery, Acta Chirurgica, 160(12), 681-687.

Gastric leiomyosarcoma : A clinicopathological review. / Sheen-Chen, S. M.; Chou, F. F.; Eng, H. L.; Chen, J. J.; Lee, C. M.; Wan, Y. L.

In: European Journal of Surgery, Acta Chirurgica, Vol. 160, No. 12, 01.01.1994, p. 681-687.

Research output: Contribution to journalArticle

Sheen-Chen, SM, Chou, FF, Eng, HL, Chen, JJ, Lee, CM & Wan, YL 1994, 'Gastric leiomyosarcoma: A clinicopathological review', European Journal of Surgery, Acta Chirurgica, vol. 160, no. 12, pp. 681-687.
Sheen-Chen SM, Chou FF, Eng HL, Chen JJ, Lee CM, Wan YL. Gastric leiomyosarcoma: A clinicopathological review. European Journal of Surgery, Acta Chirurgica. 1994 Jan 1;160(12):681-687.
Sheen-Chen, S. M. ; Chou, F. F. ; Eng, H. L. ; Chen, J. J. ; Lee, C. M. ; Wan, Y. L. / Gastric leiomyosarcoma : A clinicopathological review. In: European Journal of Surgery, Acta Chirurgica. 1994 ; Vol. 160, No. 12. pp. 681-687.
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