Fundus abnormalities in a patient with type I Gaucher's disease with 12-year follow-up

Tsung Jen Wang, Muh Shy Chen, Yung Feng Shih, Wuh Liang Hwu, Ming Yang Lai

Research output: Contribution to journalArticle

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Abstract

Purpose: To report a case of type I Gaucher's disease with rare presentation of fundus abnormalities in long-term observation. Design: Observational case report. Methods: This 53-year-old Taiwanese woman suffered from type I Gaucher's disease for 12 years, with initial presentation of hepatoslpenomegaly in 1992. Results: At that time, poor vision with unusual macular change and peripheral retinal vessel leakage was also noted. She received a complete ophthalmic examination at the initial visit and again 12 years later in 2003. She was treated with imiglucerase injection during the last 4 years. However, her visual acuity was 10/200 in both eyes. The macular and peripheral retinal degenerative change progressed after 12 years. Conclusions: Fundus changes associated with Gaucher's disease are uncommon. We should not neglect the possibility of retinal involvement and progression in these patients.

Original languageEnglish
Pages (from-to)359-362
Number of pages4
JournalAmerican Journal of Ophthalmology
Volume139
Issue number2
DOIs
Publication statusPublished - Feb 2005
Externally publishedYes

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Gaucher Disease
Retinal Vessels
Visual Acuity
Observation
Injections

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Fundus abnormalities in a patient with type I Gaucher's disease with 12-year follow-up. / Wang, Tsung Jen; Chen, Muh Shy; Shih, Yung Feng; Hwu, Wuh Liang; Lai, Ming Yang.

In: American Journal of Ophthalmology, Vol. 139, No. 2, 02.2005, p. 359-362.

Research output: Contribution to journalArticle

Wang, Tsung Jen ; Chen, Muh Shy ; Shih, Yung Feng ; Hwu, Wuh Liang ; Lai, Ming Yang. / Fundus abnormalities in a patient with type I Gaucher's disease with 12-year follow-up. In: American Journal of Ophthalmology. 2005 ; Vol. 139, No. 2. pp. 359-362.
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