Frequency domain analysis of electrooculogram and its correlation with cardiac sympathetic function

Terry B J Kuo, Cheryl C H Yang

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

To test the hypothesis that electrooculogram contains information on autonomic functions, correlation analyses of electrooculogram and heart rate variability (HRV) parameters during night sleep and over 24 h were performed on 24 healthy young volunteers (12 women and 12 men). Continuous frequency-domain analysis revealed repeated emergence of electrooculogram low-frequency power (PEOG, 0.05-0.5 Hz) during night sleep. The change in the PEOG, when natural log transformed, was graded rather than all or nothing. The PEOG was not correlated with high-frequency power (HF, 0.15-0.4 Hz) of HRV. In contrast, the PEOG was significantly correlated with R-R interval (r = - 0.46 ± 0.15; mean ± SD, P < 0.05) and low-frequency power (0.04-0.15 Hz) to HF ratio (LF/HF) of HRV (r = 0.49 ± 0.10, P < 0.05). The correlation coefficient between PEOG and R-R interval and between PEOG and LF/HF became even larger (r = - 0.68 ± 0.08 and 0.58 ± 0.09, respectively) when 24-h recordings were analyzed. There was no significant difference in the correlation between women and men. We concluded that the electrooculogram, as analyzed in the frequency domain, contains information on sympathetic activity not only during night sleep but also throughout day and night in healthy young people.

Original languageEnglish
Pages (from-to)38-45
Number of pages8
JournalExperimental Neurology
Volume217
Issue number1
DOIs
Publication statusPublished - May 2009
Externally publishedYes

Fingerprint

Electrooculography
Sleep
Heart Rate
Healthy Volunteers
Power (Psychology)

Keywords

  • 24 hours polysomnogram
  • Autonomic nervous system
  • Electoroculogram
  • Heart rate variability
  • Waking and sleep

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience

Cite this

Frequency domain analysis of electrooculogram and its correlation with cardiac sympathetic function. / Kuo, Terry B J; Yang, Cheryl C H.

In: Experimental Neurology, Vol. 217, No. 1, 05.2009, p. 38-45.

Research output: Contribution to journalArticle

@article{a84f701aca8742649119470b91b70b14,
title = "Frequency domain analysis of electrooculogram and its correlation with cardiac sympathetic function",
abstract = "To test the hypothesis that electrooculogram contains information on autonomic functions, correlation analyses of electrooculogram and heart rate variability (HRV) parameters during night sleep and over 24 h were performed on 24 healthy young volunteers (12 women and 12 men). Continuous frequency-domain analysis revealed repeated emergence of electrooculogram low-frequency power (PEOG, 0.05-0.5 Hz) during night sleep. The change in the PEOG, when natural log transformed, was graded rather than all or nothing. The PEOG was not correlated with high-frequency power (HF, 0.15-0.4 Hz) of HRV. In contrast, the PEOG was significantly correlated with R-R interval (r = - 0.46 ± 0.15; mean ± SD, P < 0.05) and low-frequency power (0.04-0.15 Hz) to HF ratio (LF/HF) of HRV (r = 0.49 ± 0.10, P < 0.05). The correlation coefficient between PEOG and R-R interval and between PEOG and LF/HF became even larger (r = - 0.68 ± 0.08 and 0.58 ± 0.09, respectively) when 24-h recordings were analyzed. There was no significant difference in the correlation between women and men. We concluded that the electrooculogram, as analyzed in the frequency domain, contains information on sympathetic activity not only during night sleep but also throughout day and night in healthy young people.",
keywords = "24 hours polysomnogram, Autonomic nervous system, Electoroculogram, Heart rate variability, Waking and sleep",
author = "Kuo, {Terry B J} and Yang, {Cheryl C H}",
year = "2009",
month = "5",
doi = "10.1016/j.expneurol.2009.01.012",
language = "English",
volume = "217",
pages = "38--45",
journal = "Experimental Neurology",
issn = "0014-4886",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Frequency domain analysis of electrooculogram and its correlation with cardiac sympathetic function

AU - Kuo, Terry B J

AU - Yang, Cheryl C H

PY - 2009/5

Y1 - 2009/5

N2 - To test the hypothesis that electrooculogram contains information on autonomic functions, correlation analyses of electrooculogram and heart rate variability (HRV) parameters during night sleep and over 24 h were performed on 24 healthy young volunteers (12 women and 12 men). Continuous frequency-domain analysis revealed repeated emergence of electrooculogram low-frequency power (PEOG, 0.05-0.5 Hz) during night sleep. The change in the PEOG, when natural log transformed, was graded rather than all or nothing. The PEOG was not correlated with high-frequency power (HF, 0.15-0.4 Hz) of HRV. In contrast, the PEOG was significantly correlated with R-R interval (r = - 0.46 ± 0.15; mean ± SD, P < 0.05) and low-frequency power (0.04-0.15 Hz) to HF ratio (LF/HF) of HRV (r = 0.49 ± 0.10, P < 0.05). The correlation coefficient between PEOG and R-R interval and between PEOG and LF/HF became even larger (r = - 0.68 ± 0.08 and 0.58 ± 0.09, respectively) when 24-h recordings were analyzed. There was no significant difference in the correlation between women and men. We concluded that the electrooculogram, as analyzed in the frequency domain, contains information on sympathetic activity not only during night sleep but also throughout day and night in healthy young people.

AB - To test the hypothesis that electrooculogram contains information on autonomic functions, correlation analyses of electrooculogram and heart rate variability (HRV) parameters during night sleep and over 24 h were performed on 24 healthy young volunteers (12 women and 12 men). Continuous frequency-domain analysis revealed repeated emergence of electrooculogram low-frequency power (PEOG, 0.05-0.5 Hz) during night sleep. The change in the PEOG, when natural log transformed, was graded rather than all or nothing. The PEOG was not correlated with high-frequency power (HF, 0.15-0.4 Hz) of HRV. In contrast, the PEOG was significantly correlated with R-R interval (r = - 0.46 ± 0.15; mean ± SD, P < 0.05) and low-frequency power (0.04-0.15 Hz) to HF ratio (LF/HF) of HRV (r = 0.49 ± 0.10, P < 0.05). The correlation coefficient between PEOG and R-R interval and between PEOG and LF/HF became even larger (r = - 0.68 ± 0.08 and 0.58 ± 0.09, respectively) when 24-h recordings were analyzed. There was no significant difference in the correlation between women and men. We concluded that the electrooculogram, as analyzed in the frequency domain, contains information on sympathetic activity not only during night sleep but also throughout day and night in healthy young people.

KW - 24 hours polysomnogram

KW - Autonomic nervous system

KW - Electoroculogram

KW - Heart rate variability

KW - Waking and sleep

UR - http://www.scopus.com/inward/record.url?scp=64549083247&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64549083247&partnerID=8YFLogxK

U2 - 10.1016/j.expneurol.2009.01.012

DO - 10.1016/j.expneurol.2009.01.012

M3 - Article

VL - 217

SP - 38

EP - 45

JO - Experimental Neurology

JF - Experimental Neurology

SN - 0014-4886

IS - 1

ER -