Frequency analysis in different types of paroxysmal atrial fibrillation

Yenn Jiang Lin, Ching Tai Tai, Tsair Kao, Han Wen Tso, Satoshi Higa, Hsuan Ming Tsao, Shih Lin Chang, Ming Hsiung Hsieh, Shih Ann Chen

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Abstract

OBJECTIVES: This study sought to investigate the regional frequency distribution from multiple bi-atrial sites in different types of paroxysmal atrial fibrillation (AF). BACKGROUND: A previous study showed a left atrium (LA) to right atrium (RA) frequency gradient in patients with paroxysmal AF. METHODS: Forty-four patients (age = 60 ± 16, male patients = 27) with paroxysmal AF originating from the pulmonary veins (PVs) (n = 31) or superior vena cava (SVC) (n = 13) were included. Frequency analysis was performed on the intracardiac electrograms (7 s, 1 kHz/channel) recorded from PV, posterior LA, coronary sinus (CS), posterolateral RA, and SVC. The largest peak frequency was identified as the dominant frequency (DF). RESULTS: In the PV-AF patients, there was a frequency gradient from the PV ostium to the LA, RA, and SVC (8.5 ± 3.3 Hz vs. 5.9 ± 1.1 Hz vs. 5.2 ± 0.85 Hz vs. 5.5 ± 0.48 Hz, respectively, p <0.001). The highest DFs were mostly located at the arrhythmogenic PV ostium (58%). The DFs of the arrhythmogenic PV and PV ostium were significantly higher than those of the non-arrhythmogenic PVs and PV ostia (p <0.05). In the SVC-AF patients, there was a frequency gradient from the SVC to the RA, LA, and PV (8.0 ± 2.4 Hz vs. 5.9 ± 1.1 Hz vs. 5.9 ± 0.7 Hz vs. 5.8 ± 0.7 Hz, respectively, p = 0.001). The highest DFs were mostly located inside the SVC (77%) instead of the SVC ostium (as compared with PV-AF patients, p = 0.035). CONCLUSIONS: The location of the highest DF depended on the arrhythmogenic PV or SVC. A frequency gradient was present between the arrhythmogenic thoracic vein and atrium in all patients.

Original languageEnglish
Pages (from-to)1401-1407
Number of pages7
JournalJournal of the American College of Cardiology
Volume47
Issue number7
DOIs
Publication statusPublished - Apr 7 2006
Externally publishedYes

ASJC Scopus subject areas

  • Nursing(all)

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  • Cite this

    Lin, Y. J., Tai, C. T., Kao, T., Tso, H. W., Higa, S., Tsao, H. M., Chang, S. L., Hsieh, M. H., & Chen, S. A. (2006). Frequency analysis in different types of paroxysmal atrial fibrillation. Journal of the American College of Cardiology, 47(7), 1401-1407. https://doi.org/10.1016/j.jacc.2005.10.071