Free radical-scavenging activity of Taiwanese native plants

W. C. Hou, R. D. Lin, K. T. Cheng, Y. T. Hung, C. H. Cho, C. H. Chen, S. Y. Hwang, M. H. Lee

Research output: Contribution to journalArticle

140 Citations (Scopus)

Abstract

The 70% aqueous acetone extracts of ten Taiwanese native plants were evaluated by various antioxidant assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl (•OH) radicals, and reducing power assay. In the present study, extracts of Acer buerferianum var. formosanum, Cleyera japonica var. morii, Cyclobalanopsis stenophylla var. stenophylloides, and Machilus zuihoensis exhibited stronger activity against DPPH radicals, and their IC50 values ranged from 5.4 to 8.3 μg/ml. The ten selected extracts effectively inhibited the formation of •OH generated in the Fenton reaction system. Among the extracts whose reducing power activities were determined, A. buerferianum var. formosanum, C. japonica var. morii, C. stenophylla var. stenophylloides, Eriobotrya deflex, and M. zuihoensis showed high activity. The results indicate the 70% aqueous acetone extracts of A. buerferianum var. formosanum, C. japonica var. morii, C. stenophylla var. stenophylloides, and M. zuihoensis with great potency in these assay systems and may be candidates for the development of natural antioxidants.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalPhytomedicine
Volume10
Issue number2-3
DOIs
Publication statusPublished - Mar 2003

Keywords

  • 1,1-diphenyl-2-picrylhydrazyl (DPPH)
  • Hydroxyl radical (•OH)
  • Reducing power
  • Taiwanese native plants

ASJC Scopus subject areas

  • Plant Science
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

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