Fluorescent probe for sequential recognition of Ga3+ and pyrophosphate anions

Chiseop Lim, Miran An, Hansol Seo, Joon Hyuk Huh, Anup Pandith, Aasif Helal, Hong Seok Kim

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Three novel fluorescent probes, 2-(2′-hydroxyphenyl)-4-chloromethylthiazole (1), 2-(2′-hydroxyphenyl)-4-hydroxymethylthiazole (3), and 2-(2′-hydroxyphenyl)-4-iodomethylthiazole (4) were designed for the sequential recognition of Ga3+ and pyrophosphate ions in acetonitrile. Probe 1 selectively detected Ga3+ through a “switch on” response, showing a good association constant (Ka = 6.24 × 104 M−1) and binding with Ga3+ ions in a 1:1 stoichiometry. An in situ generated 1-Ga3+ (1:1) ensemble detected H2P2O73–ions sequentially through a “switch off” response. The “switch on” response occurred with selective complexation of Ga3+ ions due to combined excited state intramolecular proton transfer (ESIPT) and chelation induced enhanced fluorescence (CHEF) effects. An ensemble of 1 and gallium(III) was more selective for pyrophosphate ions than any other anion.

Original languageEnglish
Pages (from-to)789-799
Number of pages11
JournalSensors and Actuators, B: Chemical
Volume241
DOIs
Publication statusPublished - Mar 31 2017
Externally publishedYes

Keywords

  • Fluorescence probe
  • Gallium ion-selective
  • Pyrophosphate
  • Sequential recognition
  • Thiazole

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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