Abstract

Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

Original languageEnglish
JournalCeramics International
DOIs
Publication statusAccepted/In press - 2017

Fingerprint

Durapatite
Hydroxyapatite
Zinc
Zinc chloride
Coatings
Coprecipitation
Biocompatibility
Bone
Flame spraying
Bioceramics
Titanium
Powders
Surgery
Fracture toughness
Sintering
Substrates
Chemical analysis
zinc chloride

Keywords

  • A: Powders: chemical preparation
  • D: Apatite
  • E: Biomedical applications

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Process Chemistry and Technology
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties. / Yang, Yung Chin; Chen, Chien Chung; Wang, Jhong Bo; Wang, Yen Ching; Lin, Feng Huei.

In: Ceramics International, 2017.

Research output: Contribution to journalArticle

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abstract = "Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.",
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AU - Yang, Yung Chin

AU - Chen, Chien Chung

AU - Wang, Jhong Bo

AU - Wang, Yen Ching

AU - Lin, Feng Huei

PY - 2017

Y1 - 2017

N2 - Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

AB - Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.

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