Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005

Cheng Hung Chiang, Wei Chun Huang, Jin Shiou Yang, Chin Chang Cheng, Feng Yu Kuo, Kuan Rau Chiou, Tao Yu Lee, Tzu Wen Lin, Guang Yuan Mar, Chuen Wang Chiou, Chun Peng Liu, King Teh Lee

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.

Original languageEnglish
Pages (from-to)387-394
Number of pages8
JournalActa Cardiologica Sinica
Volume29
Issue number5
Publication statusPublished - Sep 1 2013
Externally publishedYes

Fingerprint

Taiwan
Diabetes Mellitus
Myocardial Infarction
Infarction
Mortality
Length of Stay
Costs and Cost Analysis
National Health Programs
Percutaneous Coronary Intervention
Cardiovascular Diseases
Databases

Keywords

  • Acute myocardial infarction
  • Diabetes mellitus
  • Length of hospital stay
  • Medical cost
  • Mortality
  • National health insurance

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chiang, C. H., Huang, W. C., Yang, J. S., Cheng, C. C., Kuo, F. Y., Chiou, K. R., ... Lee, K. T. (2013). Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. Acta Cardiologica Sinica, 29(5), 387-394.

Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. / Chiang, Cheng Hung; Huang, Wei Chun; Yang, Jin Shiou; Cheng, Chin Chang; Kuo, Feng Yu; Chiou, Kuan Rau; Lee, Tao Yu; Lin, Tzu Wen; Mar, Guang Yuan; Chiou, Chuen Wang; Liu, Chun Peng; Lee, King Teh.

In: Acta Cardiologica Sinica, Vol. 29, No. 5, 01.09.2013, p. 387-394.

Research output: Contribution to journalArticle

Chiang, CH, Huang, WC, Yang, JS, Cheng, CC, Kuo, FY, Chiou, KR, Lee, TY, Lin, TW, Mar, GY, Chiou, CW, Liu, CP & Lee, KT 2013, 'Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005', Acta Cardiologica Sinica, vol. 29, no. 5, pp. 387-394.
Chiang, Cheng Hung ; Huang, Wei Chun ; Yang, Jin Shiou ; Cheng, Chin Chang ; Kuo, Feng Yu ; Chiou, Kuan Rau ; Lee, Tao Yu ; Lin, Tzu Wen ; Mar, Guang Yuan ; Chiou, Chuen Wang ; Liu, Chun Peng ; Lee, King Teh. / Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005. In: Acta Cardiologica Sinica. 2013 ; Vol. 29, No. 5. pp. 387-394.
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T1 - Five-year outcomes after acute myocardial infarction in patients with and without diabetes mellitus in Taiwan, 1996-2005

AU - Chiang, Cheng Hung

AU - Huang, Wei Chun

AU - Yang, Jin Shiou

AU - Cheng, Chin Chang

AU - Kuo, Feng Yu

AU - Chiou, Kuan Rau

AU - Lee, Tao Yu

AU - Lin, Tzu Wen

AU - Mar, Guang Yuan

AU - Chiou, Chuen Wang

AU - Liu, Chun Peng

AU - Lee, King Teh

PY - 2013/9/1

Y1 - 2013/9/1

N2 - Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.

AB - Background: Diabetes mellitus (DM) is a strong risk factor of cardiovascular disease. To date, the impact of DM on outcomes after acutemyocardial infarction (AMI) in Taiwan is undetermined. The aim of this study was to compare five-year outcomes after AMI in patients with and without diabetes in Taiwan. Methods: A nationwide cohort of 25,028 diabetic and 56,028 non-diabetic patients who were first hospitalized with AMI between 1996 and 2005 was enrolled through linkage with the Taiwan National Health Insurance research database. Patient mortality rates within 30 days after AMI, and 1, 3, and 5 years thereafter were compared. Result: Length of hospital stay (8.9 ± 8.7 vs. 8.2 ± 8.0 days, p < 0.01) and medical cost during admission (in Taiwan dollars: $129,123 ± $158,073 vs. $121,631 ± $157,018, p < 0.01) were significantly higher in diabetic patients. The difference in mortality rate within 30 days was insignificant between diabetic and non-diabetic patients (18.1% vs. 17.6%, p = 0.06). Mortalities within 1 year (31.0% vs. 26.8%, p < 0.01), 3 years (42.4% vs. 34.7%, p < 0.01), and 5 years (50.6% vs. 41.1%, p < 0.01)were significantly higher in diabetic patients. In patients with AMIwho underwent percutaneous coronary intervention (PCI) during index admission, the mortality rate within 30 days was insignificant (6.3% vs. 6.4%, p = 0.70) but mortalities within 1 year (15.2% vs. 11.6%, p < 0.01), 3 years (24.1% vs. 17.2%, p < 0.01), and 5 years (32.2% vs. 22.6%, p < 0.01) were significantly higher in diabetic patients. Conclusions: The average patient length of hospital stay and medical cost during admission were significantly higher in diabetic patients. Additionally, the difference in mortality rate within 30 days after AMI was insignificant between diabetic and non-diabetic patients. Also, long-term mortality after AMI was significantly higher in diabetic patients.

KW - Acute myocardial infarction

KW - Diabetes mellitus

KW - Length of hospital stay

KW - Medical cost

KW - Mortality

KW - National health insurance

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