Five insights from the Global Burden of Disease Study 2019

Christopher J.L. Murray, Cristiana Abbafati, Kaja M. Abbas, Mohammad Abbasi, Mohsen Abbasi-Kangevari, Foad Abd-Allah, Mohammad Abdollahi, Parisa Abedi, Aidin Abedi, Hassan Abolhassani, Victor Aboyans, Lucas Guimarães Abreu, Michael R.M. Abrigo, Eman Abu-Gharbieh, Abdulaziz Khalid Abu Haimed, Abdelrahman I. Abushouk, Alyssa Acebedo, Ilana N. Ackerman, Maryam Adabi, Abdu A. AdamuOladimeji M. Adebayo, Jaimie D. Adelson, Olatunji O. Adetokunboh, Mohsen Afarideh, Ashkan Afshin, Gina Agarwal, Anurag Agrawal, Tauseef Ahmad, Keivan Ahmadi, Mehdi Ahmadi, Muktar Beshir Ahmed, Budi Aji, Tomi Akinyemiju, Blessing Akombi, Fares Alahdab, Khurshid Alam, Fahad Mashhour Alanezi, Turki M. Alanzi, Samuel B. Albertson, Biresaw Wassihun Alemu, Yihun Mulugeta Alemu, Khalid F. Alhabib, Muhammad Ali, Saqib Ali, Gianfranco Alicandro, Vahid Alipour, Hesam Alizade, Syed Mohamed Aljunid, François Alla, Peter Allebeck, Majid Abdulrahman Hamad Almadi, Amir Almasi-Hashiani, Hesham M. Al-Mekhlafi, Abdulaziz M. Almulhim, Jordi Alonso, Rajaa M. Al-Raddadi, Khalid A. Altirkawi, Nelson Alvis-Guzman, Bekalu Amare, Azmeraw T. Amare, Saeed Amini, Arianna Maever L. Amit, Dickson A. Amugsi, Etsay Woldu Anbesu, Robert Ancuceanu, Deanna Anderlini, Jason A. Anderson, Tudorel Andrei, Catalina Liliana Andrei, Mina Anjomshoa, Fereshteh Ansari, Alireza Ansari-Moghaddam, Carl Abelardo T. Antonio, Catherine M. Antony, Davood Anvari, Seth Christopher Yaw Appiah, Jalal Arabloo, Morteza Arab-Zozani, Aleksandr Y. Aravkin, Aseb Arba Kinfe Arba, Timur Aripov, Johan Ärnlöv, Oluwaseyi Olalekan Arowosegbe, Malke Asaad, Mehran Asadi-Aliabadi, Ali A. Asadi-Pooya, Charlie Ashbaugh, Michael Assmus, Maha Moh d.Wahbi Atout, Marcel Ausloos, Floriane Ausloos, Beatriz Paulina Ayala Quintanilla, Getinet Ayano, Martin Amogre Ayanore, Samad Azari, Zelalem Nigussie Azene, Darshan B. B, Ebrahim Babaee, Alaa Badawi, Ashish D. Badiye, Mojtaba Bagherzadeh, Mohan Bairwa, Ahad Bakhtiari, Shankar M. Bakkannavar, Arun Balachandran, Maciej Banach, Srikanta K. Banerjee, Palash Chandra Banik, Adhanom Gebreegziabher Baraki, Suzanne Lyn Barker-Collo, Huda Basaleem, Sanjay Basu, Bernhard T. Baune, Mohsen Bayati, Bayisa Abdissa Baye, Neeraj Bedi, Ettore Beghi, Michellr L. Bell, Isabela M. Bensenor, Kidanemaryam Berhe, Adam E. Berman, Akshaya Srikanth Bhagavathula, Neeraj Bhala, Pankaj Bhardwaj, Krittika Bhattacharyya, Suraj Bhattarai, Zulfiqar A. Bhutta, Ali Bijani, Boris Bikbov, Antonio Biondi, Catherine Bisignano, Raaj Kishore Biswas, Tone Bjørge, Somayeh Bohlouli, Mehdi Bohluli, Srinivasa Rao Rao Bolla, Archith Boloor, Dipan Bose, Soufiane Boufous, Oliver J. Brady, Dejana Braithwaite, Michael Brauer, Nicholas J.K. Breitborde, Hermann Brenner, Alexey V. Breusov, Paul Svitil Briant, Andrew M. Briggs, Gabrielle B. Britton, Traolach Brugha, Sharath Burugina Nagaraja, Reinhard Busse, Zahid A. Butt, Florentino Luciano Caetano dos Santos, Luis LA Alberto Cámera, Ismael R. Campos-Nonato, Julio Cesar Campuzano Rincon, Josip Car, Rosario Cárdenas, Giulia Carreras, Juan J. Carrero, Felix Carvalho, Joao Mauricio Castaldelli-Maia, Giulio Castelpietra, Franz Castro, Ferrán Catalá-López, Kate Causey, Christopher R. Cederroth, Kelly M. Cercy, Ester Cerin, Joht Singh Chandan, Jung Chen Chang, Jaykaran Charan, Fiona J. Charlson, Vijay Kumar Chattu, Sarika Chaturvedi, Nicolas Cherbuin, Ken Lee Chin, Jesus Lorenzo Chirinos-Caceres, Daniel Youngwhan Cho, Jee Young Jasmine Choi, Dinh Toi Chu, Sheng Chia Chung, Michael T. Chung, Flavia M. Cicuttini, Massimo Cirillo, Beniamino Cislaghi, Aaron J. Cohen, Kelly Compton, Barbara Corso, Paolo Angelo Cortesi, Vera Marisa Costa, Ewerton Cousin, Richard G. Cowden, Marita Cross, Christopher Stephen Crowe, Steven Cummins, Haijiang Dai, Hancheng Dai, Giovanni Damiani, Lalit Dandona, Rakhi Dandona, Parnaz Daneshpajouhnejad, Aso Mohammad Darwesh, Jai K. Das, Rajat Das Gupta, José das Neves, Gail Davey, Claudio Alberto Dávila-Cervantes, Adrian C. Davis, Diego De Leo, Edgar Denova-Gutiérrez, Kebede Deribe, Nikolaos Dervenis, Rupak Desai, Keshab Deuba, Govinda Prasad Dhungana, Mostafa Dianatinasab, Daniel Diaz, Martin Dichgans, Alireza Didarloo, Ilse N. Dippenaar, Klara Dokova, Christiane Dolecek, Fariba Dorostkar, Pratik P. Doshi, Chirag P. Doshi, Leila Doshmangir, Matthew C. Doxey, Tim Robert Driscoll, Bruce B. Duncan, Arielle Wilder Eagan, Hedyeh Ebrahimi, Mohammad Ebrahimi Kalan, David Edvardsson, Joshua R. Ehrlich, Iffat Elbarazi, Islam Y. Elgendy, Shaimaa I. El-Jaafary, Maysaa El Sayed Zaki, Aisha Elsharkawy, Maha El Tantawi, Iqbal RF Elyazar, Mohammad Hassan Emamian, Babak Eshrati, Sharareh Eskandarieh, Alireza Esteghamati, Sadaf Esteghamati, Jessica Fanzo, Andre Faro, Farshad Farzadfar, Nazir Fattahi, Valery L. Feigin, Seyed Mohammad Fereshtehnejad, Eduarda Fernandes, Pietro Ferrara, Alize J. Ferrari, Irina Filip, Florian Fischer, James L. Fisher, Ryan Fitzgerald, Nataliya A. Foigt, Morenike Oluwatoyin Folayan, Artem Alekseevich Fomenkov, Masoud Foroutan, Richard Charles Franklin, Marisa Freitas, Takeshi Fukumoto, João M. Furtado, Mohamed M. Gad, Abhay Motiramji Gaidhane, Emmanuela Gakidou, Silvano Gallus, William M. Gardner, Biniyam Sahiledengle Geberemariyam, Ketema Bizuwork Gebremedhin, Leake G. Gebremeskel, Begashaw Melaku Gebresillassie, Yilma Chisha Dea Geramo, Hailay Abrha Gesesew, Peter W. Gething, Kebede Embaye Gezae, Keyghobad Ghadiri, Fatemeh Ghaffarifar, Mansour Ghafourifard, Farhad Ghamari, Ahmad Ghashghaee, Asadollah Gholamian, Simona Giampaoli, Paramjit Singh Gill, Richard F. Gillum, Ibrahim Abdelmageed Ginawi, Giorgia Giussani, Elena V. Gnedovskaya, Myron Anthony Godinho, Mahaveer Golechha, Philimon N. Gona, Sameer Vali Gopalani, Giuseppe Gorini, Bárbara Niegia Garcia Goulart, Alessandra C. Goulart, Ayman Grada, Felix Greaves, Nachiket Gudi, Rafael Alves Guimarães, Yuming Guo, Subodh Sharan Gupta, Rajeev Gupta, Rahul Gupta, Juanita A. Haagsma, Vladimir Hachinski, Nima Hafezi-Nejad, Lydia M. Haile, Arvin Haj-Mirzaian, Brian J. Hall, Randah R. Hamadeh, Samer Hamidi, Chieh Han, Graeme J. Hankey, Josep Maria Haro, Ahmed I. Hasaballah, Abdiwahab Hashi, Amr Hassan, Soheil Hassanipour, Hadi Hassankhani, Rasmus J. Havmoeller, Simon I. Hay, Khezar Hayat, Andualem Henok, Nathaniel J. Henry, Claudiu Herteliu, Fatemeh Heydarpour, Hung Chak Ho, Michael K. Hole, Ramesh Holla, Praveen Hoogar, Kathleen Pillsbury Hopf, H. Dean Hosgood, Naznin Hossain, Mehdi Hosseinzadeh, Mihaela Hostiuc, Sorin Hostiuc, Mowafa Househ, Damian G. Hoy, Guoqing Hu, Tanvir M. Huda, Fernando N. Hugo, Ayesha Humayun, Rabia Hussain, Bing Fang Hwang, Ivo Iavicoli, Charles Ugochukwu Ibeneme, Segun Emmanuel Ibitoye, Kevin S. Ikuta, Olayinka Stephen Ilesanmi, Irena M. Ilic, Milena D. Ilic, Leeberk Raja Inbaraj, Usman Iqbal, Seyed Sina Naghibi Irvani, M. Mofizul Islam, Sheikh Mohammed Shariful Islam, Hiroyasu Iso, Chidozie C.D. Iwu, Jalil Jaafari, Deepa Jahagirdar, Mohammad Ali Jahani, Mihajlo Jakovljevic, Amir Jalali, Farzad Jalilian, Manthan Dilipkumar Janodia, Tahereh Javaheri, Ensiyeh Jenabi, Ravi Prakash Jha, Vivekanand Jha, John S. Ji, Catherine Owens Johnson, Jost B. Jonas, Mikk Jürisson, Ali Kabir, Zubair Kabir, Rizwan Kalani, Leila R. Kalankesh, Rohollah Kalhor, Tanuj Kanchan, Neeti Kapoor, Behzad Karami Matin, André Karch, Mohd Anisul Karim, Salah Eddin Karimi, Ayele Semachew Kasa, Nicholas J. Kassebaum, Gbenga A. Kayode, Ali Kazemi Karyani, Peter Keiyoro, Nauman Khalid, Mohammad Khammarnia, Maseer Khan, Ejaz Ahmad Khan, Gulfaraz Khan, Khaled Khatab, Mona M. Khater, Mahalaqua Nazli Khatib, Habibolah Khazaie, Abdullah T. Khoja, Jagdish Khubchandani, Neda Kianipour, Christian Kieling, Young Eun Kim, Yun Jin Kim, Ruth W. Kimokoti, Yohannes Kinfu, Sezer Kisa, Adnan Kisa, Niranjan Kissoon, Mika Kivimäki, Cameron J. Kneib, Megan Knight, David S.Q. Koh, Hamidreza Komaki, Jacek A. Kopec, Soewarta Kosen, Anirudh Kotlo, Parvaiz A. Koul, Ai Koyanagi, Kewal Krishan, Kris J. Krohn, Shaji KS, G. Anil Kumar, Nithin Kumar, Manasi Kumar, Om P. Kurmi, Dian Kusuma, Hmwe Hmwe Kyu, Ben Lacey, Dharmesh Kumar Lal, Ratilal Lalloo, Tea Lallukka, Qing Lan, Iván Landires, Heidi Jane Larson, Savita Lasrado, Kathryn Mei Ming Lau, Paolo Lauriola, Carlo La Vecchia, Lisiane F. Leal, Janet L. Leasher, Jorge R. Ledesma, Paul H. Lee, Shaun Wen Huey Lee, Matilde Leonardi, Janni Leung, Bingyu Li, Shanshan Li, Lee Ling Lim, Ro Ting Lin, Stefan Listl, Xuefeng Liu, Yang Liu, Giancarlo Logroscino, Jaifred Christian F. Lopez, Stefan Lorkowski, Rafael Lozano, Alton Lu, Alessandra Lugo, Raimundas Lunevicius, Ronan A. Lyons, Jianing Ma, Daiane Borges Machado, Emilie R. Maddison, Phetole Walter Mahasha, Morteza Mahmoudi, Azeem Majeed, Venkatesh Maled, Shokofeh Maleki, Afshin Maleki, Reza Malekzadeh, Deborah Carvalho Malta, Abdullah A. Mamun, Helena Manguerra, Borhan Mansouri, Mohammad Ali Mansournia, Ana M. Mantilla Herrera, Santi Martini, Francisco Rogerlândio Martins-Melo, Ira Martopullo, Seyedeh Zahra Masoumi, Benjamin Ballard Massenburg, Manu Raj Mathur, Pallab K. Maulik, Mohsen Mazidi, Colm McAlinden, John J. McGrath, Martin McKee, Man Mohan Mehndiratta, Fereshteh Mehri, Kala M. Mehta, Addisu Melese, Ziad A. Memish, Walter Mendoza, Ritesh G. Menezes, Endalkachew Worku Mengesha, Tuomo J. Meretoja, Atte Meretoja, Tomislav Mestrovic, Bartosz Miazgowski, Irmina Maria Michalek, George J. Milne, Mohammad Miri, Andreea Mirica, Erkin M. Mirrakhimov, Hamed Mirzaei, Maryam Mirzaei, Mehdi Mirzaei-Alavijeh, Awoke Temesgen Misganaw, Babak Moazen, Masoud Moghadaszadeh, Bahram Mohajer, Osama Mohamad, Yousef Mohammad, Dara K. Mohammad, Naser Mohammad Gholi Mezerji, Abdollah Mohammadian-Hafshejani, Shafiu Mohammed, Farnam Mohebi, Ali H. Mokdad, Mariam Molokhia, Lorenzo Monasta, Meghan D. Mooney, Masoud Moradi, Ghobad Moradi, Maziar Moradi-Lakeh, Rahmatollah Moradzadeh, Paula Moraga, Lidia Morawska, Joana Morgado-da-Costa, Shane Douglas Morrison, Abbas Mosapour, Jonathan F. Mosser, Seyyed Meysam Mousavi, Amin Mousavi Khaneghah, Ulrich Otto Mueller, Erin C. Mullany, Kamarul Imran Musa, Mehdi Naderi, Ahamarshan Jayaraman Nagarajan, Mohsen Naghavi, Behshad Naghshtabrizi, Mukhammad David Naimzada, Farid Najafi, Luigi Naldi, Vinod C. Nayak, Javad Nazari, Rawlance Ndejjo, Ionut Negoi, Ruxandra Irina Negoi, Henok Biresaw Netsere Netsere, Georges Nguefack-Tsague, Josephine W. Ngunjiri, Diep Ngoc Nguyen, Huong Lan Thi Nguyen, Emma Nichols, Yeshambel T. Nigatu, Rajan Nikbakhsh, Molly R. Nixon, Chukwudi A. Nnaji, Shuhei Nomura, Jean Jacques Noubiap, Christoph Nowak, Elaine Okanyene Nsoesie, Virginia Nunez-Samudio, Felix Akpojene Ogbo, Onome Bright Oghenetega, Emmanuel Wandera Okunga, Morteza Oladnabi, Andrew T. Olagunju, Jacob Olusegun Olusanya, Bolajoko Olubukunola Olusanya, Ahmed Omar Bali, Muktar Omer Omer, Sokking Ong, Kanyin L. Ong, Obinna E. Onwujekwe, Eyal Oren, Alberto Ortiz, Samuel M. Ostroff, Adrian Oţoiu, Nikita Otstavnov, Stanislav S. Otstavnov, Simon Øverland, Mayowa O. Owolabi, Mahesh P A, Jagadish Rao Padubidri, Smita Pakhale, Keyvan Pakshir, Raffaele Palladino, Adrian Pana, Songhomitra Panda-Jonas, Priya G.Kumari Parmar, Mona Pathak, George C. Patton, Hamidreza Pazoki Toroudi, Amy E. Peden, Veincent Christian Filipino Pepito, Emmanuel K. Peprah, David M. Pereira, Alexandre Pereira, Jeevan Pereira, Norberto Perico, Julia Moreira Pescarini, Hai Quang Pham, Michael R. Phillips, Cristiano Piccinelli, Tessa M. Pilz, Marina Pinheiro, Michael A. Piradov, Meghdad Pirsaheb, Farhad Pishgar, Constance Dimity Pond, Maarten J. Postma, Faheem Hyder Pottoo, Hadi Pourjafar, Farshad Pourmalek, Sergio I. Prada, Narayan Prasad, Dimas Ria Angga Pribadi, Elisabetta Pupillo, Zahiruddin Quazi Syed, Navid Rabiee, Mohammad Rabiee, Amir Radfar, Ata Rafiee, Alberto Raggi, Mohammad Hifz Ur Rahman, Muhammad Aziz Rahman, Kiana Ramezanzadeh, Chhabi Lal Ranabhat, Annemarei Ranta, Sowmya J. Rao, Puja C. Rao, Davide Rasella, Vahid Rashedi, Prateek Rastogi, Salman Rawaf, David Laith Rawaf, Lal Rawal, Reza Rawassizadeh, Ramu Rawat, Christian Razo, Lemma Demissie Regassa, Marissa Bettay Reitsma, Giuseppe Remuzzi, Vishnu Renjith, Andre M.N. Renzaho, Serge Resnikoff, Nima Rezaei, Negar Rezaei, Mohammad sadegh Rezai, Aziz Rezapour, Phoebe Anne Rhinehart, Seyed Mohammad Riahi, Antonio Luiz P. Ribeiro, Daniel Cury Ribeiro, Jennifer Rickard, Leonardo Roever, Michele Romoli, Luca Ronfani, Gholamreza Roshandel, Enrico Rubagotti, Susan Fred Rumisha, Godfrey M. Rwegerera, Seyedmohammad Saadatagah, Siamak Sabour, Perminder S. Sachdev, Basema Saddik, Masoumeh Sadeghi, Ehsan Sadeghi, Sahar Saeedi Moghaddam, Amirhossein Sahebkar, Mohammad Ali Sahraian, S. Mohammad Sajadi, Marwa R.Rashad Salem, Hosni Salem, Hamideh Salimzadeh, Joshua A. Salomon, Inbal Salz, Zainab Samad, Hossein Samadi Kafil, Abdallah M. Samy, Juan Sanabria, Damian Francesco Santomauro, Milena M. Santric-Milicevic, Sivan Yegnanarayana Iyer Saraswathy, Nizal Sarrafzadegan, Benn Sartorius, Arash Sarveazad, Brijesh Sathian, Thirunavukkarasu Sathish, Davide Sattin, Lauren E. Schaeffer, Silvia Schiavolin, Maria Inês Schmidt, Aletta Elisabeth Schutte, David C. Schwebel, Falk Schwendicke, Sadaf G. Sepanlou, Feng Sha, Omid Shafaat, Saeed Shahabi, Amira A. Shaheen, Masood Ali Shaikh, Mehran Shams-Beyranvand, Morteza Shamsizadeh, Kiomars Sharafi, Fablina Sharara, Aziz Sheikh, B. Suresh Kumar Shetty, Kenji Shibuya, Mika Shigematsu, Min Jeong Shin, Jae Il Shin, Rahman Shiri, K. M. 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Tela, Mohamad Hani Temsah, Sonyah Terrason, Bhaskar Thakur, Kavumpurathu Raman Thankappan, Rekha Thapar, Nihal Thomas, Mariya Vladimirovna Titova, Boikhutso Tlou, Marcello Tonelli, Roman Topor-Madry, Anna E. Torre, Mathilde Touvier, Marcos Roberto Roberto Tovani-Palone, Bach Xuan Tran, Ravensara Travillian, Riaz Uddin, Irfan Ullah, Bhaskaran Unnikrishnan, Era Upadhyay, Marco Vacante, Regina Vaicekonyte, Pascual R. Valdez, Alessandro Valli, Tommi Juhani Vasankari, Yasser Vasseghian, Narayanaswamy Venketasubramanian, Simone Vidale, Francesco S. Violante, Vasily Vlassov, Stein Emil Vollset, Avina Vongpradith, Giang Thu Vu, Feleke Gebremeskel W/hawariat, Yasir Waheed, Richard G. Wamai, Fang Wang, Haidong Wang, Jiayu Wang, Yanzhong Wang, Yuan Pang Wang, Alexandrea Watson, Jingkai Wei, Robert G. Weintraub, Jordan Weiss, Fissaha Tekulu Welay, Andrea Werdecker, Ronny Westerman, Harvey A. Whiteford, Taweewat Wiangkham, Nuwan Darshana Wickramasinghe, Lauren B. Wilner, Bogdan Wojtyniak, Charles D.A. Wolfe, Temesgen Gebeyehu Wondmeneh, Ai Min Wu, Chenkai Wu, Sarah Wulf Hanson, Han Yong Wunrow, Yang Xie, Seyed Hossein Yahyazadeh Jabbari, Kazumasa Yamagishi, Sanni Yaya, Vahid Yazdi-Feyzabadi, Jamal A. Yearwood, Tomas Y. Yeheyis, Yordanos Gizachew Yeshitila, Paul Yip, Naohiro Yonemoto, Seok Jun Yoon, Mustafa Z. Younis, Theodore Patrick Younker, Taraneh Yousefinezhadi, Chuanhua Yu, Yong Yu, Deniz Yuce, Hasan Yusefzadeh, Syed Saoud Zaidi, Sojib Bin Zaman, Maryam Zamanian, Alireza Zangeneh, Hadi Zarafshan, Mikhail Sergeevich Zastrozhin, Kaleab Alemayehu Zewdie, Zhi Jiang Zhang, Jianrong Zhang, Yunquan Zhang, Xiu Ju George Zhao, Yingxi Zhao, Bistra Zheleva, Peng Zheng, Cong Zhu, Arash Ziapour, Stephanie R.M. Zimsen, Alan D. Lopez, Theo Vos, Stephen S. Lim

Research output: Contribution to journalReview articlepeer-review

61 Citations (Scopus)

Abstract

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3·5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.

Original languageEnglish
Pages (from-to)1135-1159
Number of pages25
JournalThe Lancet
Volume396
Issue number10258
DOIs
Publication statusPublished - Oct 17 2020

ASJC Scopus subject areas

  • Medicine(all)

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