Fever of unknown origin in Taiwan

C. Chin, Y. S. Chen, S. S J Lee, S. R. Wann, H. H. Lin, W. R. Lin, C. K. Huang, H. C. Tsai, C. H. Kao, M. Y. Yen, Y. C. Liu

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background: Fever of unknown origin (FUO) is a challenging problem worldwide. There was no prospective study of FUO in the past two decades in Taiwan. A prospective study was conducted. Materials and Methods: The prospective study was undertaken from March 2001 to May 2002. All patients fulfilling the modified criteria for FUO, either admitted, referred or consulted in a medical center in southern Taiwan, were enrolled for analysis. Results: A total of 94 cases met the criteria of FUO. The final diagnoses of FUO consisted of 54 infectious diseases (57.4%), 8 hematologic/neoplastic (8.5%), 7 noninfectious inflammatory (7.4%), 8 miscellaneous (8.5%) and 17 undiagnosed (18.1%) cases. The single most common cause of FUO was tuberculosis. Some infectious diseases, such as rickettsiosis and melioidosis, were rarely reported in western countries. Three patients with hemophagocytotic syndrome without ascertainable etiologies were present with FUO in this study. Between the patients with and those without a final diagnosis, the short-term survival (3 months) was compared by the Kaplan-Meier analysis, which revealed no difference. Conclusions: Mycobacteriosis is still the leading cause of FUO in Taiwan and it is important to identify this treatable disease from all causes of FUO. This study has showed geographical variation among the studies of FUO.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalInfection
Volume34
Issue number2
DOIs
Publication statusPublished - Apr 2006
Externally publishedYes

Fingerprint

Fever of Unknown Origin
Taiwan
Prospective Studies
Communicable Diseases
Melioidosis
Kaplan-Meier Estimate
Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Chin, C., Chen, Y. S., Lee, S. S. J., Wann, S. R., Lin, H. H., Lin, W. R., ... Liu, Y. C. (2006). Fever of unknown origin in Taiwan. Infection, 34(2), 75-80. https://doi.org/10.1007/s15010-006-5010-2

Fever of unknown origin in Taiwan. / Chin, C.; Chen, Y. S.; Lee, S. S J; Wann, S. R.; Lin, H. H.; Lin, W. R.; Huang, C. K.; Tsai, H. C.; Kao, C. H.; Yen, M. Y.; Liu, Y. C.

In: Infection, Vol. 34, No. 2, 04.2006, p. 75-80.

Research output: Contribution to journalArticle

Chin, C, Chen, YS, Lee, SSJ, Wann, SR, Lin, HH, Lin, WR, Huang, CK, Tsai, HC, Kao, CH, Yen, MY & Liu, YC 2006, 'Fever of unknown origin in Taiwan', Infection, vol. 34, no. 2, pp. 75-80. https://doi.org/10.1007/s15010-006-5010-2
Chin C, Chen YS, Lee SSJ, Wann SR, Lin HH, Lin WR et al. Fever of unknown origin in Taiwan. Infection. 2006 Apr;34(2):75-80. https://doi.org/10.1007/s15010-006-5010-2
Chin, C. ; Chen, Y. S. ; Lee, S. S J ; Wann, S. R. ; Lin, H. H. ; Lin, W. R. ; Huang, C. K. ; Tsai, H. C. ; Kao, C. H. ; Yen, M. Y. ; Liu, Y. C. / Fever of unknown origin in Taiwan. In: Infection. 2006 ; Vol. 34, No. 2. pp. 75-80.
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