Abstract
Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.
| Original language | English |
|---|---|
| Pages (from-to) | 157-160 |
| Number of pages | 4 |
| Journal | Fertility and Sterility |
| Volume | 66 |
| Issue number | 1 |
| Publication status | Published - Jan 1 1996 |
| Externally published | Yes |
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Keywords
- defective spermiogenesis
- Intracytoplasmic spermatid injection
- obstructive azoospermia
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology
Cite this
Chen, S. U., Ho, H. N., Chen, H. F., Tsai, T. C., Lee, T. Y., & Yang, Y. S. (1996). Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis. Fertility and Sterility, 66(1), 157-160.