Abstract
Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.
| Original language | English |
|---|---|
| Pages (from-to) | 157-160 |
| Number of pages | 4 |
| Journal | Fertility and Sterility |
| Volume | 66 |
| Issue number | 1 |
| Publication status | Published - Jan 1 1996 |
| Externally published | Yes |
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Keywords
- defective spermiogenesis
- Intracytoplasmic spermatid injection
- obstructive azoospermia
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology
Cite this
Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis. / Chen, S. U.; Ho, H. N.; Chen, H. F.; Tsai, T. C.; Lee, T. Y.; Yang, Y. S.
In: Fertility and Sterility, Vol. 66, No. 1, 01.01.1996, p. 157-160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fertilization and embryo cleavage after intracytoplasmic spermatid injection in an obstructive azoospermic patient with defective spermiogenesis
AU - Chen, S. U.
AU - Ho, H. N.
AU - Chen, H. F.
AU - Tsai, T. C.
AU - Lee, T. Y.
AU - Yang, Y. S.
PY - 1996/1/1
Y1 - 1996/1/1
N2 - Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.
AB - Objective: To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. Design: Clinical trial. Setting: Reproductive unit of a university teaching hospital. Patient: A patient of obstructive azoospermia with defective spermiogenesis. Intervention: Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. Main Outcome Measures: Fertilization and cleavage. Results: Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. Conclusion: Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.
KW - defective spermiogenesis
KW - Intracytoplasmic spermatid injection
KW - obstructive azoospermia
UR - http://www.scopus.com/inward/record.url?scp=0029942297&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029942297&partnerID=8YFLogxK
M3 - Article
C2 - 8752630
AN - SCOPUS:0029942297
VL - 66
SP - 157
EP - 160
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 1
ER -