Fatigue patterns and correlates in male liver cancer patients receiving transcatheter hepatic arterial chemoembolization

Shiow Ching Shun, Yeur Hur Lai, Ting Ting Jing, Chii Jeng, Fa Yau Lee, Li Shia Hu, Sue-Yueh Cheng

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Liver cancer is a leading cancer in Taiwan, especially in males. Transcatheter arterial chemoembolization (TACE) is a major treatment for these patients, but research examining their fatigue experiences is limited. The purposes of this longitudinal, correlational study were to identify (1) changes in fatigue, symptom distress, anxiety and depression in cancer patients across four time points during the first week of TACE treatment, and (2) factors predicting changes in fatigue across the four time points. Eligible male inpatients with liver cancer were recruited from a medical center in Taipei. Subjects (n=40) were assessed 1 day before (T1), and during days 2 (T2), 4 (T3) and 6 (T4) of TACE. Data were analyzed by descriptive statistics, Pearson's correlations, repeated measures analysis of variance (ANOVA) and the generalized estimating equation (GEE). Subjects had mild to moderate levels of fatigue that peaked at T2, and showed a decrease at T3 and T4 but were still slightly higher than at T1. The GEE analysis showed that greater symptom distress, anxiety and depression, higher Adriamycin dosage, longer duration of previous fatigue, and less education significantly predicted fatigue changes. The results indicate that the pattern of fatigue in TACE during the first week is similar to fatigue in patients receiving chemotherapy. The results also further indicate that fatigue is associated to several factors. The causal relationships between fatigue and these related factors should be examined. Interventions targeting these factors should also be tested in future studies.

Original languageEnglish
Pages (from-to)311-317
Number of pages7
JournalSupportive Care in Cancer
Volume13
Issue number5
DOIs
Publication statusPublished - May 2005

Fingerprint

Liver Neoplasms
Fatigue
Liver
Anxiety
Depression
Taiwan
Doxorubicin
Longitudinal Studies
Inpatients
Neoplasms
Analysis of Variance
Education
Drug Therapy
Therapeutics

Keywords

  • Anxiety
  • Depression
  • Fatigue pattern
  • Liver cancer
  • Symptom distress

ASJC Scopus subject areas

  • Oncology
  • Nursing(all)

Cite this

Fatigue patterns and correlates in male liver cancer patients receiving transcatheter hepatic arterial chemoembolization. / Shun, Shiow Ching; Lai, Yeur Hur; Jing, Ting Ting; Jeng, Chii; Lee, Fa Yau; Hu, Li Shia; Cheng, Sue-Yueh.

In: Supportive Care in Cancer, Vol. 13, No. 5, 05.2005, p. 311-317.

Research output: Contribution to journalArticle

Shun, Shiow Ching ; Lai, Yeur Hur ; Jing, Ting Ting ; Jeng, Chii ; Lee, Fa Yau ; Hu, Li Shia ; Cheng, Sue-Yueh. / Fatigue patterns and correlates in male liver cancer patients receiving transcatheter hepatic arterial chemoembolization. In: Supportive Care in Cancer. 2005 ; Vol. 13, No. 5. pp. 311-317.
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