Fasting Serum Total Ghrelin Level Inversely Correlates with Metabolic Syndrome in Hemodialysis Patients

Chia Chi Lee, Ru Ping Lee, Yi Maun Subeq, Chih Hsien Wang, Te Chao Fang, Bang Gee Hsu

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Background: Metabolic syndrome (MS) is a significant risk factor for cardiovascular disease and predicts hospitalization in patients undergoing hemodialysis. An inverse association between circulating ghrelin and MS has been observed in adults. However, no data are available on the relationship between MS and serum total ghrelin levels in hemodialysis patients. Methods: Fasting blood samples were obtained from 52 hemodialysis patients. MS and its components were defined using diagnostic criteria from the International Diabetes Federation. Total ghrelin levels were measured using a commercial enzyme-linked immunosorbent assay kit. Results: Of the 52 hemodialysis patients, 30 (58%) had MS. Fasting total ghrelin level inversely correlated with MS among these hemodialysis patients (p 2 change = 0.297, p

Original languageEnglish
Pages (from-to)785-790
Number of pages6
JournalArchives of Medical Research
Volume39
Issue number8
DOIs
Publication statusPublished - Nov 2008
Externally publishedYes

Keywords

  • Ghrelin
  • Hemodialysis
  • Metabolic syndrome
  • Waist circumference

ASJC Scopus subject areas

  • Medicine(all)

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