Familial hypertensive intracerebral hemorrhage and autosomal dominant polycystic kidney disease

Tien Jen Lin, Fu Chao Hwang, Chien Jen Chen, Wen Ta Chiu, Cheng Kuei Chang

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a generalized disease known to be associated with intracranial aneurysms. Non-aneurysmal intracerebral hemorrhage (ICH) has also been reported in ADPKD. We report a familial clustering of ICH and symptomatic ADPKD. This pedigree had at least six affected family members who suffered from ADPKD, hypertension and non-aneurysmal ICH. The proband demonstrated ADPKD, hypertension and cerebral hemorrhage. To our knowledge, this is the first report of familial ICH in ADPKD, which may have underlying genetic and environmental etiologies.

Original languageEnglish
Pages (from-to)474-477
Number of pages4
JournalJournal of Clinical Neuroscience
Volume12
Issue number4
DOIs
Publication statusPublished - May 2005

Keywords

  • Autosomal dominant polycystic kidney disease
  • Cerebral hemorrhage
  • Hypertension

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Neurology

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