Factors that influence the operative mortality after blunt hepatic injuries

R. J. Chen, J. F. Fang, B. C. Lin, Y. D. Wang, M. F. Chen

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective: To analyse causes of death and possible factors that influenced the operative mortality in patients with blunt hepatic injuries. Design: Retrospective case study. Setting: Medical center, Taiwan. Patients: 109 adult patients with blunt hepatic injuries were treated surgically over the four year period from September 1987 to August 1991. Main outcome measure: Mortality. Results: 36 patients (33%) had hepatorrhaphy or no repair, complex repairs were done for 73 patients (67%) and the overall mortality was 22% (24/109). Of those deaths, however, 4 were not liver-related, giving us a liver-related mortality of 19% (20/105). Fourteen of the liver-related deaths occurred within 24 hours of injury of hemorrhagic shock or coagulopathy. Six occurred after 24 hours of sepsis and multiple system organ failure. Multivariate analysis showed that higher initial aspartate aminotransferase (AST) and Injury Severity Score as well as increasing operative blood loss resulted in a worsening prognosis. Conclusion: The initial AST activity and Injury Severity Score as well as the total operative blood loss were the significant factors that influenced the operative mortality after blunt hepatic injuries in our study. Prompt, expeditious, and appropriate surgical management to control operative loss is the only way for the surgeon to reduce the mortality of blunt hepatic injuries.

Original languageEnglish
Pages (from-to)811-817
Number of pages7
JournalEuropean Journal of Surgery, Acta Chirurgica
Volume161
Issue number11
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Nonpenetrating Wounds
Mortality
Liver
Injury Severity Score
Aspartate Aminotransferases
Multiple Organ Failure
Hemorrhagic Shock
Taiwan
Cause of Death
Sepsis
Multivariate Analysis
Retrospective Studies
Outcome Assessment (Health Care)
Wounds and Injuries

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Factors that influence the operative mortality after blunt hepatic injuries. / Chen, R. J.; Fang, J. F.; Lin, B. C.; Wang, Y. D.; Chen, M. F.

In: European Journal of Surgery, Acta Chirurgica, Vol. 161, No. 11, 1995, p. 811-817.

Research output: Contribution to journalArticle

Chen, R. J. ; Fang, J. F. ; Lin, B. C. ; Wang, Y. D. ; Chen, M. F. / Factors that influence the operative mortality after blunt hepatic injuries. In: European Journal of Surgery, Acta Chirurgica. 1995 ; Vol. 161, No. 11. pp. 811-817.
@article{77aaaf8f3bb74f87b101b949b1f02506,
title = "Factors that influence the operative mortality after blunt hepatic injuries",
abstract = "Objective: To analyse causes of death and possible factors that influenced the operative mortality in patients with blunt hepatic injuries. Design: Retrospective case study. Setting: Medical center, Taiwan. Patients: 109 adult patients with blunt hepatic injuries were treated surgically over the four year period from September 1987 to August 1991. Main outcome measure: Mortality. Results: 36 patients (33{\%}) had hepatorrhaphy or no repair, complex repairs were done for 73 patients (67{\%}) and the overall mortality was 22{\%} (24/109). Of those deaths, however, 4 were not liver-related, giving us a liver-related mortality of 19{\%} (20/105). Fourteen of the liver-related deaths occurred within 24 hours of injury of hemorrhagic shock or coagulopathy. Six occurred after 24 hours of sepsis and multiple system organ failure. Multivariate analysis showed that higher initial aspartate aminotransferase (AST) and Injury Severity Score as well as increasing operative blood loss resulted in a worsening prognosis. Conclusion: The initial AST activity and Injury Severity Score as well as the total operative blood loss were the significant factors that influenced the operative mortality after blunt hepatic injuries in our study. Prompt, expeditious, and appropriate surgical management to control operative loss is the only way for the surgeon to reduce the mortality of blunt hepatic injuries.",
author = "Chen, {R. J.} and Fang, {J. F.} and Lin, {B. C.} and Wang, {Y. D.} and Chen, {M. F.}",
year = "1995",
language = "English",
volume = "161",
pages = "811--817",
journal = "British Journal of Surgery",
issn = "0007-1323",
publisher = "John Wiley and Sons Ltd",
number = "11",

}

TY - JOUR

T1 - Factors that influence the operative mortality after blunt hepatic injuries

AU - Chen, R. J.

AU - Fang, J. F.

AU - Lin, B. C.

AU - Wang, Y. D.

AU - Chen, M. F.

PY - 1995

Y1 - 1995

N2 - Objective: To analyse causes of death and possible factors that influenced the operative mortality in patients with blunt hepatic injuries. Design: Retrospective case study. Setting: Medical center, Taiwan. Patients: 109 adult patients with blunt hepatic injuries were treated surgically over the four year period from September 1987 to August 1991. Main outcome measure: Mortality. Results: 36 patients (33%) had hepatorrhaphy or no repair, complex repairs were done for 73 patients (67%) and the overall mortality was 22% (24/109). Of those deaths, however, 4 were not liver-related, giving us a liver-related mortality of 19% (20/105). Fourteen of the liver-related deaths occurred within 24 hours of injury of hemorrhagic shock or coagulopathy. Six occurred after 24 hours of sepsis and multiple system organ failure. Multivariate analysis showed that higher initial aspartate aminotransferase (AST) and Injury Severity Score as well as increasing operative blood loss resulted in a worsening prognosis. Conclusion: The initial AST activity and Injury Severity Score as well as the total operative blood loss were the significant factors that influenced the operative mortality after blunt hepatic injuries in our study. Prompt, expeditious, and appropriate surgical management to control operative loss is the only way for the surgeon to reduce the mortality of blunt hepatic injuries.

AB - Objective: To analyse causes of death and possible factors that influenced the operative mortality in patients with blunt hepatic injuries. Design: Retrospective case study. Setting: Medical center, Taiwan. Patients: 109 adult patients with blunt hepatic injuries were treated surgically over the four year period from September 1987 to August 1991. Main outcome measure: Mortality. Results: 36 patients (33%) had hepatorrhaphy or no repair, complex repairs were done for 73 patients (67%) and the overall mortality was 22% (24/109). Of those deaths, however, 4 were not liver-related, giving us a liver-related mortality of 19% (20/105). Fourteen of the liver-related deaths occurred within 24 hours of injury of hemorrhagic shock or coagulopathy. Six occurred after 24 hours of sepsis and multiple system organ failure. Multivariate analysis showed that higher initial aspartate aminotransferase (AST) and Injury Severity Score as well as increasing operative blood loss resulted in a worsening prognosis. Conclusion: The initial AST activity and Injury Severity Score as well as the total operative blood loss were the significant factors that influenced the operative mortality after blunt hepatic injuries in our study. Prompt, expeditious, and appropriate surgical management to control operative loss is the only way for the surgeon to reduce the mortality of blunt hepatic injuries.

UR - http://www.scopus.com/inward/record.url?scp=0028882154&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028882154&partnerID=8YFLogxK

M3 - Article

VL - 161

SP - 811

EP - 817

JO - British Journal of Surgery

JF - British Journal of Surgery

SN - 0007-1323

IS - 11

ER -