Fabrication of surface enhanced raman scattering (SERS)-active substrates by using dip-pen nanolithography

Fei-Peng Lee, K. Chao, K. H. Hsieh, Keng-Liang Ou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this study, we propose an effective strategy to prepare a stable surface enhanced Raman scattering (SERS)-active substrate by using dip-pen nanolithography (DPN) with top-down wet chemical etching. This method was made by DPN to pattern arrays, 16- mercaplohexadecaoic acid (MHA) on Au/Cr/Si substrates and then ferri/ferrocyanide etching was adopted to remove the exposed gold. It is found that a nanostructure with φ 300 nm gold dots and the distance between dot and dot is 400 nm can be obtained on the surface of substrates after etching. These nanostructure gold dots can enhance local electromagnetic fields, inducing enhancement of analytes' Raman signal. This process supplies the effective and stable SERS-active substrate which can be used as biomedical applications, such as protein chip, and microorganisms' discrimination chip.

Original languageEnglish
Title of host publicationECS Transactions
Pages301-305
Number of pages5
Volume50
Edition12
DOIs
Publication statusPublished - 2012
EventSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012 - Honolulu, HI, United States
Duration: Oct 7 2012Oct 12 2012

Other

OtherSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012
CountryUnited States
CityHonolulu, HI
Period10/7/1210/12/12

ASJC Scopus subject areas

  • Engineering(all)

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