Extensive cerebrospinal fluid enhancement following gadolinium chelate administration

Possible pathogenesis

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Diffuse cerebrospinal fluid (CSF) enhancement following gadolinium administration is a rarely recognized phenomenon, and its mechanism is not fully understood. We report two cases of diffuse CSF enhancement following gadolinium administration and review the literature. We conclude that the contributing factors of this phenomenon include blood-CSF barrier disruption, increased dosage, impair renal clearance, delayed imaging after contrast administration, and use of different pulse sequences.

Original languageEnglish
Pages (from-to)523-527
Number of pages5
JournalActa Radiologica
Volume46
Issue number5
DOIs
Publication statusPublished - Aug 2005
Externally publishedYes

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Gadolinium
Cerebrospinal Fluid
Kidney

Keywords

  • Blood-brain barrier
  • Gadolinium
  • Leptomeningeal enhancement
  • Magnetic resonance images

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

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abstract = "Diffuse cerebrospinal fluid (CSF) enhancement following gadolinium administration is a rarely recognized phenomenon, and its mechanism is not fully understood. We report two cases of diffuse CSF enhancement following gadolinium administration and review the literature. We conclude that the contributing factors of this phenomenon include blood-CSF barrier disruption, increased dosage, impair renal clearance, delayed imaging after contrast administration, and use of different pulse sequences.",
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AU - Chen, C. J.

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N2 - Diffuse cerebrospinal fluid (CSF) enhancement following gadolinium administration is a rarely recognized phenomenon, and its mechanism is not fully understood. We report two cases of diffuse CSF enhancement following gadolinium administration and review the literature. We conclude that the contributing factors of this phenomenon include blood-CSF barrier disruption, increased dosage, impair renal clearance, delayed imaging after contrast administration, and use of different pulse sequences.

AB - Diffuse cerebrospinal fluid (CSF) enhancement following gadolinium administration is a rarely recognized phenomenon, and its mechanism is not fully understood. We report two cases of diffuse CSF enhancement following gadolinium administration and review the literature. We conclude that the contributing factors of this phenomenon include blood-CSF barrier disruption, increased dosage, impair renal clearance, delayed imaging after contrast administration, and use of different pulse sequences.

KW - Blood-brain barrier

KW - Gadolinium

KW - Leptomeningeal enhancement

KW - Magnetic resonance images

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