Extensive cerebrospinal fluid enhancement following gadolinium chelate administration: Possible pathogenesis

Hui-Ling Hsu, C. J. Chen

Research output: Contribution to journalArticle

6 Citations (Scopus)


Diffuse cerebrospinal fluid (CSF) enhancement following gadolinium administration is a rarely recognized phenomenon, and its mechanism is not fully understood. We report two cases of diffuse CSF enhancement following gadolinium administration and review the literature. We conclude that the contributing factors of this phenomenon include blood-CSF barrier disruption, increased dosage, impair renal clearance, delayed imaging after contrast administration, and use of different pulse sequences.

Original languageEnglish
Pages (from-to)523-527
Number of pages5
JournalActa Radiologica
Issue number5
Publication statusPublished - Aug 2005
Externally publishedYes



  • Blood-brain barrier
  • Gadolinium
  • Leptomeningeal enhancement
  • Magnetic resonance images

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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