[Expression and clinical significance of circadian gene Per2 in non-small cell lung cancer].

Chuang Chi, Zhi feng He, Y. Liu, Xiao ming Lin, Cheng chao Sun

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4 Citations (Scopus)


To detect the expression of Per2 in non-small cell lung cancer (NSCLC), and analyze its clinical significance. The expression of Per2 was determined in 60 NSCLC and 20 normal lung tissues by immunohistochemical assay, and the relationship between Per2 expression and clinicopathological features was analyzed. The positive expression rates of Per2 in NSCLC and normal lung tissues were 71.7% and 95.0%, respectively (P < 0.05). The expression of Per2 in NSCLC was correlated with pathological differentiation and TNM stage (P < 0.05). The expression of Per2 in NSCLC is decreased. The negative expression of Per2 may contribute to the development and invasion in NSCLC.

Original languageEnglish
Pages (from-to)129-131
Number of pages3
JournalChinese Journal of Oncology
Issue number2
Publication statusPublished - Jan 1 2013
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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