Exposure to combustion of solid fuel and tuberculosis: A matched case - Control study

M. Gninafon, G. Ade, N. Aït-Khaled, Donald A. Enarson, Chen-Yuan Chiang

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The present study was conducted in Benin to ascertain the association between exposure to combustion of solid fuel (coal and biomass) and tuberculosis. Cases were consecutive, sputum smear-positive tuberculosis patients never previously treated for tuberculosis for as long as 1 month. Two controls were selected from the neighbourhood of each case, matched by age and sex by a predefined procedure. A total of 200 new smear-positive cases and 400 neighbourhood controls were enrolled. In univariate analysis, using solid fuel for cooking (OR 1.7, 95% CI 1.1-2.8), ever smoking (OR 5.5, 95% CI 3.1-9.8), male sex (OR 10.5, 95% CI 1.6-71.1), daily use of alcoholic beverages (OR 2.3, 95% CI 1.2-4.2) and having a family member with tuberculosis in the previous 5 yrs (OR 30.5, 95% CI 10.8-85.8) were all significantly associated with tuberculosis cases. When all significant variables were entered into a multivariate conditional logistic regression model, the association between using solid fuel for cooking and tuberculosis cases was no longer statistically significant (adjusted OR 1.4, 95% CI 0.7-2.7). In conclusion, the association between exposure to combustion of solid fuel and tuberculosis was relatively weak and not statistically significant. Copyright

Original languageEnglish
Pages (from-to)132-138
Number of pages7
JournalEuropean Respiratory Journal
Volume38
Issue number1
DOIs
Publication statusPublished - Jul 1 2011

Fingerprint

Case-Control Studies
Tuberculosis
Cooking
Logistic Models
Benin
Alcoholic Beverages
Coal
Sputum
Biomass
Smoking

Keywords

  • Biomass
  • Fossil fuels
  • Indoor air pollution
  • Risk factors
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Exposure to combustion of solid fuel and tuberculosis : A matched case - Control study. / Gninafon, M.; Ade, G.; Aït-Khaled, N.; Enarson, Donald A.; Chiang, Chen-Yuan.

In: European Respiratory Journal, Vol. 38, No. 1, 01.07.2011, p. 132-138.

Research output: Contribution to journalArticle

Gninafon, M. ; Ade, G. ; Aït-Khaled, N. ; Enarson, Donald A. ; Chiang, Chen-Yuan. / Exposure to combustion of solid fuel and tuberculosis : A matched case - Control study. In: European Respiratory Journal. 2011 ; Vol. 38, No. 1. pp. 132-138.
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