Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites

Lien-Guo Dai, Keng-Yen Fu, Pai-Shan Hsieh, Yu-Min Hung, Yi-Wen Wang, Li-Chaun Hsia, Shun-Cheng Chang, Chih-Hsin Wang, Shou-Cheng Teng, Shyi-Gen Chen, Tim-Mo Chen, Niann-Tzyy Dai

Research output: Contribution to journalArticle

Abstract

Introduction. Autologous skin transplantation is a common treatment for patients with full-thickness burns. Postoperative wound care is essential for skin graft donor and recipient sites, but traditional wound dressings such as cotton and gauze do not form an effective barrier to bacteria, and patients can feel uncomfortable when replacing dressings. Materials and Methods. The goal of this study was to evaluate the use of an antimicrobial spray dressing (JUC Spray Dressing, NMS Technologies Co Ltd, Nanjing, China), with respect to its antimicrobial efficiency and the degree of pain experienced by patients. Results. The authors found the antimicrobial spray can reduce pain during the recovery period, while providing equivalent antibacterial protection to the control treatment (AQUACEL Hydrofiber Wound Dressing, ConvaTec, Bridgewater, NJ) based on skin culture tests. The spray did not adversely affect the wound site recovery. No significant side effects were present during the treatment period. Conclusion. This antimicrobial spray could potentially be used in wound dressing applications.
Original languageEnglish
Pages (from-to)224-228
Number of pages5
JournalWounds
Volume27
Issue number8
Publication statusPublished - 2015

Fingerprint

Bandages
Wound Healing
Tissue Donors
Skin
Wounds and Injuries
Pain
Skin Transplantation
Postoperative Care
Autologous Transplantation
Skin Tests
Burns
China
Therapeutics
Technology
Bacteria
Transplants

Keywords

  • antimicrobial efficiency
  • antimicrobial spray
  • full-thickness burn
  • pain
  • wound dressing

Cite this

Dai, L-G., Fu, K-Y., Hsieh, P-S., Hung, Y-M., Wang, Y-W., Hsia, L-C., ... Dai, N-T. (2015). Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites. Wounds, 27(8), 224-228.

Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites. / Dai, Lien-Guo; Fu, Keng-Yen; Hsieh, Pai-Shan; Hung, Yu-Min; Wang, Yi-Wen; Hsia, Li-Chaun; Chang, Shun-Cheng; Wang, Chih-Hsin; Teng, Shou-Cheng; Chen, Shyi-Gen; Chen, Tim-Mo; Dai, Niann-Tzyy.

In: Wounds, Vol. 27, No. 8, 2015, p. 224-228.

Research output: Contribution to journalArticle

Dai, L-G, Fu, K-Y, Hsieh, P-S, Hung, Y-M, Wang, Y-W, Hsia, L-C, Chang, S-C, Wang, C-H, Teng, S-C, Chen, S-G, Chen, T-M & Dai, N-T 2015, 'Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites', Wounds, vol. 27, no. 8, pp. 224-228.
Dai L-G, Fu K-Y, Hsieh P-S, Hung Y-M, Wang Y-W, Hsia L-C et al. Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites. Wounds. 2015;27(8):224-228.
Dai, Lien-Guo ; Fu, Keng-Yen ; Hsieh, Pai-Shan ; Hung, Yu-Min ; Wang, Yi-Wen ; Hsia, Li-Chaun ; Chang, Shun-Cheng ; Wang, Chih-Hsin ; Teng, Shou-Cheng ; Chen, Shyi-Gen ; Chen, Tim-Mo ; Dai, Niann-Tzyy. / Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites. In: Wounds. 2015 ; Vol. 27, No. 8. pp. 224-228.
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title = "Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites",
abstract = "Introduction. Autologous skin transplantation is a common treatment for patients with full-thickness burns. Postoperative wound care is essential for skin graft donor and recipient sites, but traditional wound dressings such as cotton and gauze do not form an effective barrier to bacteria, and patients can feel uncomfortable when replacing dressings. Materials and Methods. The goal of this study was to evaluate the use of an antimicrobial spray dressing (JUC Spray Dressing, NMS Technologies Co Ltd, Nanjing, China), with respect to its antimicrobial efficiency and the degree of pain experienced by patients. Results. The authors found the antimicrobial spray can reduce pain during the recovery period, while providing equivalent antibacterial protection to the control treatment (AQUACEL Hydrofiber Wound Dressing, ConvaTec, Bridgewater, NJ) based on skin culture tests. The spray did not adversely affect the wound site recovery. No significant side effects were present during the treatment period. Conclusion. This antimicrobial spray could potentially be used in wound dressing applications.",
keywords = "antimicrobial efficiency, antimicrobial spray, full-thickness burn, pain, wound dressing",
author = "Lien-Guo Dai and Keng-Yen Fu and Pai-Shan Hsieh and Yu-Min Hung and Yi-Wen Wang and Li-Chaun Hsia and Shun-Cheng Chang and Chih-Hsin Wang and Shou-Cheng Teng and Shyi-Gen Chen and Tim-Mo Chen and Niann-Tzyy Dai",
note = "Export Date: 21 March 2016 通訊地址: Dai, N.-T.; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Cheng-Kung Road, Taiwan 參考文獻: Gu, J., Liu, N., Yang, X., Feng, Z., Qi, F., Adiposed-derived stem cells seeded on plcl/p123 eletrospun nanofibrous scaffold enhance wound healing (2014) Biomed Mater, 9 (3), p. 035012; Ghosh, S.J., Kumar, K., Gilbert, P.M., Opsite spray: Its use for fixation of meshed skin grafts (1997) Simple and Low Tech. Burns, 23 (7-8), pp. 601-603; Jellish, W.S., Gamelli, R.L., Furry, P.A., McGill, V.L., Fluder, E.M., Effect of topical local anesthetic application to skin harvest sites for pain management in burn patients undergoing skin-grafting procedures (1999) Ann Surg, 229 (1), pp. 115-120; Summer, G.J., Puntillo, K.A., Misaskowski, C., Green, P.G., Levine, J.D., Burn injury pain: The continuing challenge (2007) J Pain, 8 (7), pp. 533-548; Laila, L., Febriyenti, F., Salhimi, S.M., Baie, S., Wound healing effect of haruan (channa striatus) spray (2011) Int Wound J., 8 (5), pp. 484-491; Zhou, W., Ma, K.Q., Tang, L.H., Li, F., Huang, L., Chen, J.H., Synthesis and properties of a polymerizable quaternary ammonium salt (2014) J Appl Polym Sci, 131 (21), p. 41002; Tischer, M., Pradel, G., Ohlsen, K., Holzgrabe, U., Quaternary ammonium salts and their antimicrobial potential: Targets or nonspecific interactions (2012) ChemMedChem, 7 (1), pp. 22-31; Mu{\~n}oz-Bonilla, A., Fern{\'a}ndez-Garc{\'i}a, M., Polymeric materials with antimicrobial activity (2012) Prog Polym Sci, 37 (2), pp. 281-339; Zeng, Y., Deng, R., Yeung, B.H.S., Application of an antibacterial dressing spray in the prevention of postoperative infection in oral cancer patients: A phase 1 clinical trial (2008) Afr J Biotechnol, 7 (21), pp. 3827-3831; Wood, F.M., Kolybaba, M.L., Allen, P., The use of cultured epithelial autograft in the treatment of major burn wounds: Eleven years of clinical experience (2006) Burns, 32 (5), pp. 538-544; Wan, K.A., Ng, M.Y., Wong, Y.T., New horizon on communityacquired methicillin resistant staphylococcus aureus (ca-mrsa) skin and soft tissue infection: Nanotechnology antimicrobial spray (2011) Hong Kong J Emerg Med, 18 (6), pp. 432-436; Sen, S., Palmieri, T., Greenhalgh, D., Review of burn research for the year 2013 (2014) J Burn Care Res, 35 (5), pp. 362-368",
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T1 - Evaluation of wound healing efficacy of an antimicrobial spray dressing at skin donor sites

AU - Dai, Lien-Guo

AU - Fu, Keng-Yen

AU - Hsieh, Pai-Shan

AU - Hung, Yu-Min

AU - Wang, Yi-Wen

AU - Hsia, Li-Chaun

AU - Chang, Shun-Cheng

AU - Wang, Chih-Hsin

AU - Teng, Shou-Cheng

AU - Chen, Shyi-Gen

AU - Chen, Tim-Mo

AU - Dai, Niann-Tzyy

N1 - Export Date: 21 March 2016 通訊地址: Dai, N.-T.; Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Cheng-Kung Road, Taiwan 參考文獻: Gu, J., Liu, N., Yang, X., Feng, Z., Qi, F., Adiposed-derived stem cells seeded on plcl/p123 eletrospun nanofibrous scaffold enhance wound healing (2014) Biomed Mater, 9 (3), p. 035012; Ghosh, S.J., Kumar, K., Gilbert, P.M., Opsite spray: Its use for fixation of meshed skin grafts (1997) Simple and Low Tech. Burns, 23 (7-8), pp. 601-603; Jellish, W.S., Gamelli, R.L., Furry, P.A., McGill, V.L., Fluder, E.M., Effect of topical local anesthetic application to skin harvest sites for pain management in burn patients undergoing skin-grafting procedures (1999) Ann Surg, 229 (1), pp. 115-120; Summer, G.J., Puntillo, K.A., Misaskowski, C., Green, P.G., Levine, J.D., Burn injury pain: The continuing challenge (2007) J Pain, 8 (7), pp. 533-548; Laila, L., Febriyenti, F., Salhimi, S.M., Baie, S., Wound healing effect of haruan (channa striatus) spray (2011) Int Wound J., 8 (5), pp. 484-491; Zhou, W., Ma, K.Q., Tang, L.H., Li, F., Huang, L., Chen, J.H., Synthesis and properties of a polymerizable quaternary ammonium salt (2014) J Appl Polym Sci, 131 (21), p. 41002; Tischer, M., Pradel, G., Ohlsen, K., Holzgrabe, U., Quaternary ammonium salts and their antimicrobial potential: Targets or nonspecific interactions (2012) ChemMedChem, 7 (1), pp. 22-31; Muñoz-Bonilla, A., Fernández-García, M., Polymeric materials with antimicrobial activity (2012) Prog Polym Sci, 37 (2), pp. 281-339; Zeng, Y., Deng, R., Yeung, B.H.S., Application of an antibacterial dressing spray in the prevention of postoperative infection in oral cancer patients: A phase 1 clinical trial (2008) Afr J Biotechnol, 7 (21), pp. 3827-3831; Wood, F.M., Kolybaba, M.L., Allen, P., The use of cultured epithelial autograft in the treatment of major burn wounds: Eleven years of clinical experience (2006) Burns, 32 (5), pp. 538-544; Wan, K.A., Ng, M.Y., Wong, Y.T., New horizon on communityacquired methicillin resistant staphylococcus aureus (ca-mrsa) skin and soft tissue infection: Nanotechnology antimicrobial spray (2011) Hong Kong J Emerg Med, 18 (6), pp. 432-436; Sen, S., Palmieri, T., Greenhalgh, D., Review of burn research for the year 2013 (2014) J Burn Care Res, 35 (5), pp. 362-368

PY - 2015

Y1 - 2015

N2 - Introduction. Autologous skin transplantation is a common treatment for patients with full-thickness burns. Postoperative wound care is essential for skin graft donor and recipient sites, but traditional wound dressings such as cotton and gauze do not form an effective barrier to bacteria, and patients can feel uncomfortable when replacing dressings. Materials and Methods. The goal of this study was to evaluate the use of an antimicrobial spray dressing (JUC Spray Dressing, NMS Technologies Co Ltd, Nanjing, China), with respect to its antimicrobial efficiency and the degree of pain experienced by patients. Results. The authors found the antimicrobial spray can reduce pain during the recovery period, while providing equivalent antibacterial protection to the control treatment (AQUACEL Hydrofiber Wound Dressing, ConvaTec, Bridgewater, NJ) based on skin culture tests. The spray did not adversely affect the wound site recovery. No significant side effects were present during the treatment period. Conclusion. This antimicrobial spray could potentially be used in wound dressing applications.

AB - Introduction. Autologous skin transplantation is a common treatment for patients with full-thickness burns. Postoperative wound care is essential for skin graft donor and recipient sites, but traditional wound dressings such as cotton and gauze do not form an effective barrier to bacteria, and patients can feel uncomfortable when replacing dressings. Materials and Methods. The goal of this study was to evaluate the use of an antimicrobial spray dressing (JUC Spray Dressing, NMS Technologies Co Ltd, Nanjing, China), with respect to its antimicrobial efficiency and the degree of pain experienced by patients. Results. The authors found the antimicrobial spray can reduce pain during the recovery period, while providing equivalent antibacterial protection to the control treatment (AQUACEL Hydrofiber Wound Dressing, ConvaTec, Bridgewater, NJ) based on skin culture tests. The spray did not adversely affect the wound site recovery. No significant side effects were present during the treatment period. Conclusion. This antimicrobial spray could potentially be used in wound dressing applications.

KW - antimicrobial efficiency

KW - antimicrobial spray

KW - full-thickness burn

KW - pain

KW - wound dressing

M3 - Article

VL - 27

SP - 224

EP - 228

JO - Wounds

JF - Wounds

SN - 1044-7946

IS - 8

ER -