Evaluation of antioxidants using an arachidonic acid-stimulated platelet electron spin resonance system

Kuo Hsien Hsieh, Jie Jen Lee, Lin Wen Lee, Joen Rong Sheu, Su Tzy Hwang, Duen Suey Chou

Research output: Contribution to journalArticle


A novel cell-containing assay system using electron spin resonance (ESR) and spin-trapping methods was established. We used this assay system to evaluate the antioxidant activities of various dietary antioxidants including resveratrol, lycopene, quercetin and rutin. Resveratrol showed the strongest radical-scavenging activity among the compounds tested. Our results provided useful data for the establishment of a model for evaluating the antioxidant activities of natural dietary substances in cell-containing systems.

Original languageEnglish
JournalJournal of Food and Drug Analysis
Issue number3
Publication statusPublished - Sep 2011



  • Arachidonic acid
  • Carbon-centered radical
  • Electron spin resonance
  • Hydroxyl radical
  • Platelets

ASJC Scopus subject areas

  • Food Science
  • Pharmacology

Cite this