Evaluation of accuracy of FAD-GDH- and mutant Q-GDH-based blood glucose monitors in multi-patient populations

Ta Yu Huang, Hui Wen Chang, Mei Fen Tsao, Shu Ming Chuang, Chih Chin Ni, Jun Wei Sue, Hsiu Chen Lin, Cheng Teng Hsu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Glucose dehydrogenases have been highly promoted to high-accuracy blood glucose (BG) monitors. The flavin adenine dinucleotide glucose dehydrogenase (FAD-GDH) and mutant variant of quinoprotein glucose dehydrogenase (Mut. Q-GDH) are widely used in high-performance BG monitors for multi-patient use. Therefore we conducted accuracy evaluation of the GDH monitors, FAD-GDH-based GM700 and Mut. Q-GDH-based Performa. Methods: Different patients were enrolled: patients with and without diabetes, patients receiving respiratory therapies, hemodialysis (HD) and peritoneal dialysis (PD) patients, and neonates. The accuracy evaluation of FAD-GDH- and Mut. Q-GDH-based monitors referred to ISO 15197:2013 which applies new criteria for the minion accuracy requirements: more than 95% of the blood glucose readings shall fall within ±. 15. mg/dL of the reference method at glucose concentration

Original languageEnglish
Pages (from-to)28-33
Number of pages6
JournalClinica Chimica Acta
Volume433
DOIs
Publication statusPublished - Jun 10 2014

Fingerprint

glucose dehydrogenase (pyrroloquinoline-quinone)
Glucose 1-Dehydrogenase
Flavin-Adenine Dinucleotide
Blood Glucose
Respiratory therapy
Glucose Dehydrogenases
Population
Dialysis
Medical problems
Respiratory Therapy
Glucose
Peritoneal Dialysis
Renal Dialysis
Reading
Newborn Infant

Keywords

  • Arterial blood
  • Blood glucose monitoring system
  • Glucose dehydrogenase
  • Hemodialysis
  • ISO 15197:2013
  • Neonate

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical
  • Medicine(all)

Cite this

Huang, T. Y., Chang, H. W., Tsao, M. F., Chuang, S. M., Ni, C. C., Sue, J. W., ... Hsu, C. T. (2014). Evaluation of accuracy of FAD-GDH- and mutant Q-GDH-based blood glucose monitors in multi-patient populations. Clinica Chimica Acta, 433, 28-33. https://doi.org/10.1016/j.cca.2014.02.023

Evaluation of accuracy of FAD-GDH- and mutant Q-GDH-based blood glucose monitors in multi-patient populations. / Huang, Ta Yu; Chang, Hui Wen; Tsao, Mei Fen; Chuang, Shu Ming; Ni, Chih Chin; Sue, Jun Wei; Lin, Hsiu Chen; Hsu, Cheng Teng.

In: Clinica Chimica Acta, Vol. 433, 10.06.2014, p. 28-33.

Research output: Contribution to journalArticle

Huang, Ta Yu ; Chang, Hui Wen ; Tsao, Mei Fen ; Chuang, Shu Ming ; Ni, Chih Chin ; Sue, Jun Wei ; Lin, Hsiu Chen ; Hsu, Cheng Teng. / Evaluation of accuracy of FAD-GDH- and mutant Q-GDH-based blood glucose monitors in multi-patient populations. In: Clinica Chimica Acta. 2014 ; Vol. 433. pp. 28-33.
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