Ethanol extract of Dunaliella salina induces cell cycle arrest and apoptosis in A549 human non-small cell lung cancer cells

Ming Jyh Sheu, Guan Jhong Huang, Chieh Hsi Wu, Jwo Sheng Chen, Heng Yuan Chang, Shu Jen Chang, Jing Gung Chung

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The ethanol extract of Dunaliella salina (EDS) on proliferation and apoptosis in the A549 human lung cancer cell line and their associated protein expressions were investigated. After 24 and 48 h treatment, MTT assay showed that 25 μg/ml of EDS significantly reduced A549 cell proliferation by 25.2% (p

Original languageEnglish
Pages (from-to)369-378
Number of pages10
JournalIn Vivo
Volume22
Issue number3
Publication statusPublished - May 2008
Externally publishedYes

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Cell Cycle Checkpoints
Non-Small Cell Lung Carcinoma
Ethanol
Cells
Apoptosis
Cell proliferation
Assays
Lung Neoplasms
Cell Proliferation
Cell Line
Proteins
Salinum
A549 Cells

Keywords

  • β-carotene
  • A549
  • Apoptosis
  • Dunaliella salina
  • NSCLS
  • p53

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sheu, M. J., Huang, G. J., Wu, C. H., Chen, J. S., Chang, H. Y., Chang, S. J., & Chung, J. G. (2008). Ethanol extract of Dunaliella salina induces cell cycle arrest and apoptosis in A549 human non-small cell lung cancer cells. In Vivo, 22(3), 369-378.

Ethanol extract of Dunaliella salina induces cell cycle arrest and apoptosis in A549 human non-small cell lung cancer cells. / Sheu, Ming Jyh; Huang, Guan Jhong; Wu, Chieh Hsi; Chen, Jwo Sheng; Chang, Heng Yuan; Chang, Shu Jen; Chung, Jing Gung.

In: In Vivo, Vol. 22, No. 3, 05.2008, p. 369-378.

Research output: Contribution to journalArticle

Sheu, MJ, Huang, GJ, Wu, CH, Chen, JS, Chang, HY, Chang, SJ & Chung, JG 2008, 'Ethanol extract of Dunaliella salina induces cell cycle arrest and apoptosis in A549 human non-small cell lung cancer cells', In Vivo, vol. 22, no. 3, pp. 369-378.
Sheu, Ming Jyh ; Huang, Guan Jhong ; Wu, Chieh Hsi ; Chen, Jwo Sheng ; Chang, Heng Yuan ; Chang, Shu Jen ; Chung, Jing Gung. / Ethanol extract of Dunaliella salina induces cell cycle arrest and apoptosis in A549 human non-small cell lung cancer cells. In: In Vivo. 2008 ; Vol. 22, No. 3. pp. 369-378.
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