Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999

Chung Guei Huang, Kuo Chien Tsao, Tzou Yien Lin, Yhu Chering Huang, Li Ang Lee, Tzu Hou Chen, Ya Ling Huang, Shin Ru Shih

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Abstract

Human metapneumovirus (hMPV) causes both upper and lower respiratory tract infection worldwide. Because little is known about the estimated level of exposure to hMPV in Taiwan, data for 1999 are presented. One thousand one hundred twenty sera from otherwise healthy community-based subjects aged 1 month to 99 years were tested in an enzyme-linked immunosorbent assay; the proportion of seropositive individuals was 68.1%. Moreover, 53.2% of preschool children were seronegative, whereas 88.3% of school-aged individuals and 93.7% of adults had antibodies to hMPV. In summary, the present study provides an earlier evidence of a high rate of exposure to hMPV characterized the seroprevalence among Taiwanese individuals in 1999. In addition, our findings suggest that preschool children in particular would benefit from vaccination against hMPV.

Original languageEnglish
Pages (from-to)343-350
Number of pages8
JournalArchives of Virology
Volume155
Issue number3
DOIs
Publication statusPublished - Mar 2010
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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    Huang, C. G., Tsao, K. C., Lin, T. Y., Huang, Y. C., Lee, L. A., Chen, T. H., Huang, Y. L., & Shih, S. R. (2010). Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999. Archives of Virology, 155(3), 343-350. https://doi.org/10.1007/s00705-010-0596-1