Esophageal adenocarcinoma arising from Barrett's epithelium in Taiwan

Chia Hung Tu, Ching Tai Lee, Daw Shyong Perng, Chun Chao Chang, Chih Hung Hsu, Yi Chia Lee

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6 Citations (Scopus)

Abstract

The prevalence of Barrett's esophagus (BE) in Eastern countries is rising to match the prevalence in the West. However, a corresponding trend of BE-associated adenocarcinoma has yet to be observed in Asia. Historically, adenocarcinoma complicating BE has been considered a rare event in Taiwan. In the present report, we collected three Taiwanese cases of esophageal adenocarcinoma arising from BE. The first case was a 37-year-old man with an advanced cancer that developed on pre-existing BE after a 3-year interval without endoscopic surveillance. The second case was a 63-year-old man who presented with odynophagia and was found to have an ulcerative tumor centered on the characteristic Barrett's mucosa. The final case was a 44-year-old man who presented with gradual-onset dysphagia and weight loss, without typical reflux symptom. Our report emphasizes the need for an updated epidemiologic study to determine the incidence of BE-associated adenocarcinoma in Taiwan.

Original languageEnglish
Pages (from-to)664-668
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume106
Issue number8
DOIs
Publication statusPublished - Aug 2007

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Keywords

  • Barrett's esophagus
  • Esophageal adenocarcinoma
  • Gastroesophageal reflux disease

ASJC Scopus subject areas

  • Medicine(all)

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