Erectile dysfunction, loss of libido and low sexual frequency increase the risk of cardiovascular disease in men with low testosterone

Chen-Hsun Ho, Chia Chang Wu, Kuan Chou Chen, Fu Shan Jaw, Hong Jeng Yu, Shih Ping Liu

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Introduction: Testosterone deficiency increases the cardiovascular disease (CVD) risk. Aim: To evaluate the effect of erectile dysfunction (ED), sexual frequency and hypogonadal symptoms on CVD risk. Methods: A total of 395 hypogonadal men aged 45–74 years were surveyed using the Androgen Deficiency in the Aging Male and the International Index of Erectile Function. Main outcome measures: The 10-year CVD risk was measured with the Framingham Risk Score. Logistic regression was performed to obtain the odds ratios of sexual function and hypogonadal symptoms for a 10-year CVD risk ≥20% (high risk). Results: The mean age was 56.1 ± 6.7 years. The mean 10-year CVD risk of the whole cohort was 18.1% ± 11.4%, while 131 subjects (33.2%) were classified as high risk. Logistic regression revealed that ED severity was associated with CVD risk [OR = 2.37 (CI 1.24–4.51) for mild-to-moderate ED, OR = 4.39 (1.78–8.43) for moderate ED and OR = 12.81 (4.65–26.11) for severe ED]. Compared to sexual frequency

Original languageEnglish
Pages (from-to)96-101
Number of pages6
JournalAging Male
Volume19
Issue number2
DOIs
Publication statusPublished - Apr 2 2016

Keywords

  • cardiovascular disease
  • erectile dysfunction
  • Framingham Risk Score
  • hypogonadism
  • libido
  • Testosterone

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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