Epidemiology and Prevalence of Bloodstream Infections in a Regional Hospital in Northern Taiwan During 2008-2013

Wen Shyang Hsieh, Yin Tai Tsai, Wei Ming Chi, Hsueh Hsia Wu

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28% of these sets, as follows: 5.48% exhibited growth of a single microorganism; 1.56% exhibited growth of more than one microorganism; and 3.24% exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02%); Enterobacteriaceae (56.51%); glucose nonfermentative Gram-negative bacteria (7.27%); yeast (6.22%); and anaerobic bacteria (6.64%). Most microorganisms were identified as follows: Escherichia coli (33.80%); Staphylococcus aureus (14.20%); Klebsiella pneumoniae (11.41%); Pseudomonas aeruginosa (3.17%); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68%). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.

Original languageEnglish
Pages (from-to)187-189
Number of pages3
JournalJournal of Experimental and Clinical Medicine(Taiwan)
Volume6
Issue number6
DOIs
Publication statusPublished - Dec 1 2014

Fingerprint

Taiwan
Epidemiology
Age Groups
Bacteremia
Growth
Infection
Acinetobacter calcoaceticus
Escherichia coli
Acinetobacter baumannii
Gram-Positive Cocci
Streptococcus agalactiae
Anaerobic Bacteria
Klebsiella pneumoniae
Enterobacteriaceae
Streptococcus pneumoniae
Microbiology
Gram-Negative Bacteria
Salmonella
Pseudomonas aeruginosa
Medical Records

Keywords

  • Escherichia coli
  • Group B Streptococcus
  • Infant bacteremia
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Epidemiology and Prevalence of Bloodstream Infections in a Regional Hospital in Northern Taiwan During 2008-2013. / Hsieh, Wen Shyang; Tsai, Yin Tai; Chi, Wei Ming; Wu, Hsueh Hsia.

In: Journal of Experimental and Clinical Medicine(Taiwan), Vol. 6, No. 6, 01.12.2014, p. 187-189.

Research output: Contribution to journalArticle

@article{fa827957da944dc18a7c3ad754569a81,
title = "Epidemiology and Prevalence of Bloodstream Infections in a Regional Hospital in Northern Taiwan During 2008-2013",
abstract = "Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28{\%} of these sets, as follows: 5.48{\%} exhibited growth of a single microorganism; 1.56{\%} exhibited growth of more than one microorganism; and 3.24{\%} exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02{\%}); Enterobacteriaceae (56.51{\%}); glucose nonfermentative Gram-negative bacteria (7.27{\%}); yeast (6.22{\%}); and anaerobic bacteria (6.64{\%}). Most microorganisms were identified as follows: Escherichia coli (33.80{\%}); Staphylococcus aureus (14.20{\%}); Klebsiella pneumoniae (11.41{\%}); Pseudomonas aeruginosa (3.17{\%}); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68{\%}). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.",
keywords = "Escherichia coli, Group B Streptococcus, Infant bacteremia, Staphylococcus aureus",
author = "Hsieh, {Wen Shyang} and Tsai, {Yin Tai} and Chi, {Wei Ming} and Wu, {Hsueh Hsia}",
year = "2014",
month = "12",
day = "1",
doi = "10.1016/j.jecm.2014.10.011",
language = "English",
volume = "6",
pages = "187--189",
journal = "Journal of Experimental and Clinical Medicine",
issn = "1878-3317",
publisher = "Elsevier Taiwan LLC",
number = "6",

}

TY - JOUR

T1 - Epidemiology and Prevalence of Bloodstream Infections in a Regional Hospital in Northern Taiwan During 2008-2013

AU - Hsieh, Wen Shyang

AU - Tsai, Yin Tai

AU - Chi, Wei Ming

AU - Wu, Hsueh Hsia

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28% of these sets, as follows: 5.48% exhibited growth of a single microorganism; 1.56% exhibited growth of more than one microorganism; and 3.24% exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02%); Enterobacteriaceae (56.51%); glucose nonfermentative Gram-negative bacteria (7.27%); yeast (6.22%); and anaerobic bacteria (6.64%). Most microorganisms were identified as follows: Escherichia coli (33.80%); Staphylococcus aureus (14.20%); Klebsiella pneumoniae (11.41%); Pseudomonas aeruginosa (3.17%); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68%). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.

AB - Background: Diagnosing bloodstream infections (BSIs) is a critical function of clinical microbiology laboratories. To reveal the prevalence of BSIs in a hospital in Northern Taiwan, which was established in July 2008, we investigated the clinical characteristics of patients with positive blood cultures from July 2008 to December 2013. Methods: The medical records of the patients were retrospectively reviewed. In total, 104,641 blood culture sets were collected and analyzed. Results: Microorganisms grew on 10.28% of these sets, as follows: 5.48% exhibited growth of a single microorganism; 1.56% exhibited growth of more than one microorganism; and 3.24% exhibited growth of contaminants. Furthermore, 5739 monomicrobial isolates included: Gram-positive cocci (22.02%); Enterobacteriaceae (56.51%); glucose nonfermentative Gram-negative bacteria (7.27%); yeast (6.22%); and anaerobic bacteria (6.64%). Most microorganisms were identified as follows: Escherichia coli (33.80%); Staphylococcus aureus (14.20%); Klebsiella pneumoniae (11.41%); Pseudomonas aeruginosa (3.17%); and the Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex (2.68%). Furthermore, among infants aged ≤3 months, Group B Streptococcus (GBS) and S.aureus were the leading pathogens causing bacteremia, whereas among infants 3-12 months old and children 1-4 years old, Salmonella species were the leading pathogens causing bacteremia. The prevalence of Streptococcus pneumoniae increased from the 3-12-month-old age group and reached a peak in the 5-12-year-old age group. For patients aged >13 years, the most common pathogens were E.coli, S.aureus, and K.pneumoniae. Conclusion: We propose that the types and prevalence of BSIs vary according to age group and exhibit substantial geographical differences.

KW - Escherichia coli

KW - Group B Streptococcus

KW - Infant bacteremia

KW - Staphylococcus aureus

UR - http://www.scopus.com/inward/record.url?scp=84916209836&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84916209836&partnerID=8YFLogxK

U2 - 10.1016/j.jecm.2014.10.011

DO - 10.1016/j.jecm.2014.10.011

M3 - Article

AN - SCOPUS:84916209836

VL - 6

SP - 187

EP - 189

JO - Journal of Experimental and Clinical Medicine

JF - Journal of Experimental and Clinical Medicine

SN - 1878-3317

IS - 6

ER -