Epidemiologic features and virus isolation of enteroviruses in Northern Taiwan during 2000-2008

Kuo Chien Tsao, Chung Guei Huang, Ya Ling Huang, Feng Chu Chen, Peng Nien Huang, Yuh Chering Huang, Tzou Yen Lin, Shin Ru Shih, Shih Cheng Chang

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Abstract

The susceptibility of five cell lines, RD, MRC-5, MK-2, Hep-2 and A549, for various serotypes of human enteroviruses was evaluated. RD cells were susceptible to most serotypes of enteroviruses, especially for human enterovirus A. Consequently, a high prevalence of human enterovirus A in Taiwan may reflect the relative importance of RD cells in the clinical virology laboratory. However, susceptibilities of RD cells to coxsackievirus A9 and A24, and echovirus 9 and 11 were exceptionally low. Alternatively, MRC-5 or MK-2 cells can improve the isolation of these four enteroviruses.

Original languageEnglish
Pages (from-to)330-332
Number of pages3
JournalJournal of Virological Methods
Volume165
Issue number2
DOIs
Publication statusPublished - May 2010
Externally publishedYes

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Keywords

  • Cell lines
  • Coxsackievirus
  • Echovirus
  • Human enteroviruses
  • Susceptibility

ASJC Scopus subject areas

  • Virology

Cite this

Tsao, K. C., Huang, C. G., Huang, Y. L., Chen, F. C., Huang, P. N., Huang, Y. C., Lin, T. Y., Shih, S. R., & Chang, S. C. (2010). Epidemiologic features and virus isolation of enteroviruses in Northern Taiwan during 2000-2008. Journal of Virological Methods, 165(2), 330-332. https://doi.org/10.1016/j.jviromet.2010.03.001